# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA646584 | F | Observed stimulation of the production of soluble beta-amyloid precursor protein | 5 | assay format | Scientific Literature | |||
2. | ALA649526 | B | Inhibition constant of compound on ligand binding to aggregates of Amyloid beta was measured by comparing with [125I]TZDM | 1 | single protein format | Scientific Literature | |||
3. | ALA649527 | B | Inhibition constant of compound on ligand binding to aggregates of Amyloid beta was measured by comparing with [125I]IMSB | 1 | single protein format | Scientific Literature | |||
4. | ALA649528 | B | Inhibition constant for amyloid beta compared to [125I]TZDM | Homo sapiens | 7 | single protein format | Scientific Literature | ||
5. | ALA649529 | B | Inhibition constant for aggregates of amyloid beta compared to [125I]IMSB | Homo sapiens | 7 | single protein format | Scientific Literature | ||
6. | ALA649530 | B | Inhibitory activity against binding of [125I]IMSB to amyloid beta in brain | 6 | tissue-based format | Scientific Literature | |||
7. | ALA649398 | B | Inhibition constant against [125I]-7 (TZDM) binding to Amyloid beta 1-40 aggregates | 11 | single protein format | Scientific Literature | |||
8. | ALA649399 | B | Binding affinity for Amyloid beta 1-40 aggregates fibrils in competition with BTA-1 | 1 | single protein format | Scientific Literature | |||
9. | ALA649400 | B | Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1. | 18 | single protein format | Scientific Literature | |||
10. | ALA678443 | B | Inhibition of A-beta-42 production by inhibiting Gamma-secretase proteolytic pathway in HEK293 cell stably transfected with a double mutant form of human APP(K595N/M596L) | 5 | cell-based format | Scientific Literature | |||
11. | ALA678614 | B | Inhibition of A-beta-42 production by inhibiting Gamma-secretase proteolytic pathway in HEK293 cell stably transfected with a double mutant form of human APP(K595N/M596L), at 2.5 uM concentration | 8 | cell-based format | Scientific Literature | |||
12. | ALA829742 | B | In vitro effective concentration against beta amyloid protein 40 in ELISA | Homo sapiens | 9 | single protein format | Scientific Literature | ||
13. | ALA829743 | B | In vitro effective concentration against beta amyloid protein 42 in ELISA | Homo sapiens | 4 | single protein format | Scientific Literature | ||
14. | ALA840103 | B | In vitro effective concentration against beta amyloid protein 42 in ELISA; increase in presence of weak inhibitor | Homo sapiens | 6 | single protein format | Scientific Literature | ||
15. | ALA832682 | F | In vitro inhibition of amyloid precursor protein 695 activity in CHO cells expressing human APP | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA832050 | B | Percent inhibition of beta amyloid protein 40 activity in ELISA at 100 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
17. | ALA825229 | F | In vitro elevation of beta C-terminal fragment (Ct-99) in CHO cells expressing mutant Swedish NL human APP | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA825230 | F | In vitro reduction of Swedish NL mutant amyloid precursor protein activity expressed in CHO cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA872393 | B | Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenates | 12 | tissue-based format | Scientific Literature | |||
20. | ALA881780 | B | Concentration required to inhibit A beta 40 peptide | Homo sapiens | 5 | single protein format | Scientific Literature |