| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA995905 | B | Binding affinity to HIV1 capsid protein assessed as decrease in assembly rate by turbidity-based ultraviolet spectrophotometry (RVb= 59.2+/-0.3 milliOD/min) | Human immunodeficiency virus 1 | 14 | assay format | Scientific Literature | ||
| 2. | ALA995906 | B | Binding affinity to HIV1 capsid protein assessed as assembly rate at 10 uM by turbidity-based ultraviolet spectrophotometry | Human immunodeficiency virus 1 | 2 | assay format | Scientific Literature | ||
| 3. | ALA995907 | B | Binding affinity to HIV1 capsid protein assessed as assembly rate at 20 uM by turbidity-based ultraviolet spectrophotometry | Human immunodeficiency virus 1 | 2 | assay format | Scientific Literature | ||
| 4. | ALA995908 | B | Binding affinity to HIV1 capsid protein assessed as assembly rate at 40 uM by turbidity-based ultraviolet spectrophotometry | Human immunodeficiency virus 1 | 2 | assay format | Scientific Literature | ||
| 5. | ALA960170 | B | Binding affinity to HIV1 capsid assessed as assembly rate per minute by ultraviolet spectrophotometry assay | Human immunodeficiency virus 1 | 30 | assay format | Scientific Literature | ||
| 6. | ALA960171 | B | Binding affinity to HIV1 capsid assessed as assembly rate per minute at 0.5:1 drug to protein ratio by ultraviolet spectrophotometry assay | Human immunodeficiency virus 1 | 2 | assay format | Scientific Literature | ||
| 7. | ALA960172 | B | Binding affinity to HIV1 capsid assessed as assembly rate per minute at 1:1 drug to protein ratio by ultraviolet spectrophotometry assay | Human immunodeficiency virus 1 | 2 | assay format | Scientific Literature | ||
| 8. | ALA960173 | B | Binding affinity to HIV1 capsid assessed as assembly rate per minute at 2:1 drug to protein ratio by ultraviolet spectrophotometry assay | Human immunodeficiency virus 1 | 2 | assay format | Scientific Literature | ||
| 9. | ALA1067571 | B | Binding affinity to HIV1 capsid protein assessed as viral capsid assembly rate at 1 mM by ultraviolet spectrophotometry (RVb= 60.56 +/- 3.77 milliOD/min) | Human immunodeficiency virus 1 | 21 | assay format | Scientific Literature | ||
| 10. | ALA1067572 | B | Binding affinity to HIV1 capsid protein assessed as inhibition of viral capsid assembly at 1 mM after 600 mins by turbidity-based ultraviolet spectrophotometry | Human immunodeficiency virus 1 | 4 | assay format | Scientific Literature | ||
| 11. | ALA1646259 | B | Binding affinity to HIV1 capsid protein assessed as decrease in formation of mature-like particles after 30 mins by electron microscopy | Human immunodeficiency virus 1 | 2 | assay format | Scientific Literature | ||
| 12. | ALA2214223 | B | Inhibition of HIV1 capsid protein binding to fluorescein labeled 3-(5-(3-ethyl-5-(5-methylfuran-2-yl)-1H-pyrazol-1-yl)-1-((6-oxo-1,6-dihydropyridin-3-yl)methyl)-1H-benzo[d]imidazol-2-yl)-4-hydroxybenzoic acid after 15 mins by fluorescence polarization assay | Human immunodeficiency virus 1 | 8 | assay format | Scientific Literature | ||
| 13. | ALA2214225 | B | Inhibition of HIV1 capsid protein assembly using 5'-fluorescein-labeled (TG)25 oligonucleotide after 2 hrs by fluorometry-based capsid disassembly assay | Human immunodeficiency virus 1 | 14 | assay format | Scientific Literature | ||
| 14. | ALA3060861 | B | Inhibition of Human immunodeficiency virus 1 capsid protein expressed in Escherichia coli BL21(DE3) assessed as capsid assembly rate measured every 5 secs by spectrofluorometric analysis (Rvb = 51.88 x 10'-5 OD/s) | Human immunodeficiency virus 1 | 14 | assay format | Scientific Literature | ||
| 15. | ALA2339642 | B | Inhibition of HIV1 capsid | Human immunodeficiency virus 1 | 1 | assay format | Scientific Literature | ||
| 16. | ALA2339643 | B | Binding affinity to HIV1 capsid | Human immunodeficiency virus 1 | 1 | assay format | Scientific Literature | ||
| 17. | ALA2390256 | B | Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) at 3.5 uM after 2 hrs by fluorescence assay relative to control | Human immunodeficiency virus 1 | 1 | assay format | Scientific Literature | ||
| 18. | ALA2390257 | B | Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assay | Human immunodeficiency virus 1 | 25 | assay format | Scientific Literature | ||
| 19. | ALA3772327 | B | Binding affinity to recombinant N-terminal GST-tagged HIV1 NL4-3 capsid C-terminal domain (146 to 231 residues) incubated for 2 hrs by alphascreen assay | Human immunodeficiency virus 1 | 26 | assay format | Scientific Literature | ||
| 20. | ALA3772330 | B | Binding affinity to HIV1 NL4-3 capsid C-terminal domain (146 to 231 residues) by isothermal titration calorimetry | Human immunodeficiency virus 1 | 1 | assay format | Scientific Literature |
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