| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA644292 | B | Compound was tested for its ability to inhibit acetylcholinesterase (AChE) in rat brain | 3 | ALA1134423 | tissue-based format | Scientific Literature | ||
| 2. | ALA644293 | B | Compound was tested for its ability to inhibit acetylcholinesterase (AChE) in rat brain | 3 | ALA1134423 | tissue-based format | Scientific Literature | ||
| 3. | ALA644294 | B | Compound was tested for its ability to inhibit acetylcholinesterase (AChE) in rat brain; 0.024-0.040 uM | 1 | ALA1134423 | tissue-based format | Scientific Literature | ||
| 4. | ALA642669 | B | Acetylcholinesterase (AChE) enzyme was inhibited after 12 h oral administration of 30 mg/kg of compound in rat brain ex vivo assay; A - Significant inhibitory effect observed | 1 | ALA1126449 | organism-based format | Scientific Literature | ||
| 5. | ALA642670 | B | Acetylcholinesterase (AChE) enzyme was inhibited after 2 hr oral administration of 5 mg/kg of compound in rat brain ex vivo assay; A - Inhibition observed | 1 | ALA1126449 | organism-based format | Scientific Literature | ||
| 6. | ALA875822 | B | Acetylcholinesterase (AChE) enzyme was inhibited after 4 hr oral administration of 5 mg/kg of compound in rat brain ex vivo assay; A - Inhibition observed | 1 | ALA1126449 | organism-based format | Scientific Literature | ||
| 7. | ALA642671 | B | Acetylcholinesterase (AChE) enzyme was inhibited after 8 hr oral administration of 10 mg/kg of compound in rat brain ex vivo assay; A - Inhibition observed | 1 | ALA1126449 | organism-based format | Scientific Literature | ||
| 8. | ALA642834 | B | Acetylcholinesterase (AChE) enzyme was inhibited after oral administration of 10 mg/kg of compound in rat brain ex vivo assay; NI means no inhibition | 1 | ALA1126449 | organism-based format | Scientific Literature | ||
| 9. | ALA642835 | B | Compound was evaluated in vitro in rats for the inhibition of brain (striatal) acetylcholinesterase (AChEI); NI=No inhibition | 1 | ALA1130558 | assay format | Scientific Literature | ||
| 10. | ALA642836 | B | Percent activity of rat brain acetylcholinesterase prior to reactivation on incubation for 5 hr with compound of 5 uM at 25 degrees | 1 | ALA1122429 | assay format | Scientific Literature | ||
| 11. | ALA642837 | B | Percent activity of rat brain acetylcholinesterase on 5 hours incubation with 5 uM of compound at 25 degree C followed by reactivation with 0.5 mM 2-PAM after 20h | 1 | ALA1122429 | assay format | Scientific Literature | ||
| 12. | ALA642838 | B | Percent activity of rat brain acetylcholinesterase on 5 hours of incubation with 5 uM at 25 degree C followed by reactivation occurring spontaneously after 20h | 1 | ALA1122429 | assay format | Scientific Literature | ||
| 13. | ALA642839 | B | Compound was evaluated for the dose at which it exhibits robust maximal effects for acetylcholinesterase (AChE) inhibition, following intraperitoneal administration | 1 | ALA1130558 | single protein format | Scientific Literature | ||
| 14. | ALA642840 | B | Dose required to exhibit robust maximal effect for acetylcholinesterase (AChE) inhibition following intraperitoneal administration | 1 | ALA1130558 | single protein format | Scientific Literature | ||
| 15. | ALA642841 | B | Compound was evaluated ex vivo for the inhibition of acetylcholinesterase (AChEI) one hour after oral administration | 2 | ALA1130558 | single protein format | Scientific Literature | ||
| 16. | ALA642842 | B | Effect on Acetylcholinesterase activity in rat brain homogenates | Rattus norvegicus | 11 | ALA1123058 | tissue-based format | Scientific Literature | |
| 17. | ALA642843 | B | Effect on Acetylcholinesterase activity in rat erythrocytes | Rattus norvegicus | 11 | ALA1123058 | cell-based format | Scientific Literature | |
| 18. | ALA642844 | B | Inhibitory activity against acetylcholinetransferase (AChE) enzyme | Rattus norvegicus | 28 | ALA1124268 | single protein format | Scientific Literature | |
| 19. | ALA636452 | B | In vitro inhibitory activity against Acetylcholinesterase (AChE) using rat brain hippocampal crude homogenates. | 2 | ALA1130862 | tissue-based format | Scientific Literature | ||
| 20. | ALA636453 | B | Compound was evaluated in vitro in rats for the inhibition of brain (striatal) acetylcholinesterase (AChEI) using acetylthiocholine as substrate; 0.0026-0.031 | 1 | ALA1130558 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!