# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA655889 | F | Effective concentration required against human bombesin receptor 3 (BRS-3) in CHO cells by using FLIPR assay. | 37 | ALA1145035 | cell-based format | Scientific Literature | ||
2. | ALA649926 | B | Inhibition of [125I]Tyr3-BBN binding to NCI-H1299 cell line | Homo sapiens | 1 | ALA1132692 | cell-based format | Scientific Literature | |
3. | ALA694685 | F | Compound up to a conc of 32 uM was tested for displacement of radiolabeled GRP from its receptors on bombesin-responsive human SCLC cell line N592; NA is no measurable agonist activity | Homo sapiens | 2 | ALA1126408 | cell-based format | Scientific Literature | |
4. | ALA831380 | B | Inhibition of bombesin subtype 3 receptor expressed in human lung carcinoids | Homo sapiens | 5 | ALA1145281 | assay format | Scientific Literature | |
5. | ALA998537 | F | Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLIPR assay | 23 | ALA1152231 | cell-based format | Scientific Literature | ||
6. | ALA998538 | F | Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as maximum response of intracellular calcium mobilization by FLIPR assay relative to D-Phe-Gln-Trp-Ala-Val-beta-Ala-His-Phe-Nle-NH2 | 9 | ALA1152231 | cell-based format | Scientific Literature | ||
7. | ALA998541 | B | Binding affinity to BRS-3 receptor | 1 | ALA1152231 | single protein format | Scientific Literature | ||
8. | ALA1113305 | B | Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]bombesin from human BRS3 expressed in NFAT-CHO cells after 2 hrs by liquid scintillation counting | Homo sapiens | 1 | ALA1155395 | cell-based format | Scientific Literature | |
9. | ALA1113306 | F | Agonistic activity at human BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assay | Homo sapiens | 43 | ALA1155395 | cell-based format | Scientific Literature | |
10. | ALA1113307 | F | Agonistic activity at human BRS3 expressed in HEK293AEO at 10 uM cells by aequorin bioluminescence assay relative to dY peptide | Homo sapiens | 43 | ALA1155395 | cell-based format | Scientific Literature | |
11. | ALA1116182 | B | Displacement of [125I]D-Tyr6-betaAla11-Phe13-Nle14-bombesin from human BRS-3 expressed in NFAT-CHO cells after 2 hrs by scintillation counting | Homo sapiens | 22 | ALA1156946 | cell-based format | Scientific Literature | |
12. | ALA1116183 | F | Agonist activity at human BRS-3 expressed in HEK293 cells coexpressing AEQ over 10 mins by aequorin bioluminescence assay | Homo sapiens | 22 | ALA1156946 | cell-based format | Scientific Literature | |
13. | ALA1116184 | F | Agonist activity at human BRS-3 expressed in HEK293 cells coexpressing AEQ over 10 mins by aequorin bioluminescence assay relative to D-Tyr6-betaAla11-Phe13-Nle14-bombesin | Homo sapiens | 22 | ALA1156946 | cell-based format | Scientific Literature | |
14. | ALA1110001 | B | Binding affinity to human BRS3 | Homo sapiens | 18 | ALA1157884 | single protein format | Scientific Literature | |
15. | ALA1110002 | F | Agonist activity at human BRS3 | Homo sapiens | 18 | ALA1157884 | assay format | Scientific Literature | |
16. | ALA1110003 | F | Agonist activity at human BRS3 relative to [D-Tyr6,b-Ala11,Phe13,Nle14]-Bombesin | Homo sapiens | 18 | ALA1157884 | assay format | Scientific Literature | |
17. | ALA1111911 | F | Agonist activity at human BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay | Homo sapiens | 36 | ALA1157936 | cell-based format | Scientific Literature | |
18. | ALA1111912 | F | Agonist activity at human BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay relative to dY-peptide | Homo sapiens | 35 | ALA1157936 | cell-based format | Scientific Literature | |
19. | ALA1680281 | B | Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]-Bombesin (6-14) from human BRS-3 | Homo sapiens | 6 | ALA1671827 | single protein format | Scientific Literature | |
20. | ALA1680282 | F | Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence assay | Homo sapiens | 8 | ALA1671827 | cell-based format | Scientific Literature |