# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA655973 | B | Compound was evaluated for inhibitory activity against C1s serine protease. | 2 | single protein format | Scientific Literature | |||
2. | ALA885071 | B | Inhibitory activity against human Complement C1s subcomponent in erythrocyte hemolytic assay | 1 | single protein format | Scientific Literature | |||
3. | ALA666759 | B | In vitro binding affinity towards human Complement C1s subcomponent | 39 | single protein format | Scientific Literature | |||
4. | ALA865639 | B | Inhibition of C1S | Homo sapiens | 34 | single protein format | Scientific Literature | ||
5. | ALA927223 | B | Inhibition of Complement C1s subcomponent | 23 | single protein format | Scientific Literature | |||
6. | ALA1613966 | F | PUBCHEM_BIOASSAY: Complement C1s ELISA. (Class of assay: confirmatory) [Related pubchem assays: 538, 787 ] | Homo sapiens | 21 | assay format | PubChem BioAssays | ||
7. | ALA2320209 | B | Inhibition of human C1s | Homo sapiens | 2 | single protein format | Scientific Literature | ||
8. | ALA2340451 | B | Inhibition of CCC1s (unknown origin) using Dabcyl-SLGRKIQI-EDANS substrate incubated for 15 mins prior to substrate addition measured for 2 hrs | Homo sapiens | 1 | single protein format | Scientific Literature | ||
9. | ALA2339105 | B | Inhibition of CCC1s (unknown origin) using Dabcyl-SLGRKIQI-EDANS substrate assessed as residual activity at 10 uM incubated for 15 mins prior to substrate addition measured for 2 hrs | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA3096694 | B | Inhibition of C1s (unknown origin) at 100 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA3256272 | B | Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as substrate by spectrophotometric analysis | Homo sapiens | 20 | single protein format | Scientific Literature | ||
12. | ALA3256274 | B | Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol production using N-Z-L-Lys-ONp as substrate by spectrophotometric analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
13. | ALA3578607 | B | Inhibition of C1s (unknown origin) at 100 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA3705561 | B | Inhibition Assay: Inhibition of human C1s was determined by the method described in [0092]-[0098] using native human activated C1s complement component from Calbiochem at 29 nM and Val-Ser-Arg-pNA (S2314) at 8 mM, 6 mM, and 4 mM as substrate; results are reported as Ki values (nanomolar). | Homo sapiens | 21 | single protein format | BindingDB Database | ||
15. | ALA3861695 | B | Inhibition of C1s (unknown origin) at 100 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA4038152 | B | Inhibition of recombinant human C-terminal 6His-tagged complement component C1s (1 to 688 residues) expressed in mouse NS0 cells using fluorogenic Z-Lys-SBzl peptide as substrate after 5 mins by fluorescence based assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
17. | ALA4200622 | B | Inhibition of C1S (unknown origin) at 10 nM to 33.3 uM after 30 mins by gel-based ABPP assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA4229682 | B | Inhibition of human serum C1s using AGLME as substrate after 30 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA4229683 | B | Inhibition of human C1s esterolytic activity using benzyloxycarbonyl-Lys-thiobenzyl as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA4229686 | B | Inhibition of human serum C1s-mediated lysis of rabbit Ab-sensitized sheep erythrocytes after 60 mins | Homo sapiens | 1 | assay format | Scientific Literature |