# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3423880 | Binding | Agonist activity at 5HT2A receptor (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | ALA3421577 | single protein format | Scientific Literature | |
2. | ALA3424016 | Binding | Antagonist activity at 5HT2A receptor (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA3421577 | single protein format | Scientific Literature | |
3. | ALA3425056 | Binding | Displacement of [3H]ketanserin from recombinant human 5HT2A receptor expressed in HEK293 cells at 1 uM after 60 mins by scintillation counting analysis relative to control | Homo sapiens | 1 | ALA3421625 | cell-based format | Scientific Literature | |
4. | ALA3429289 | Binding | Binding affinity to human 5HT-2A receptor assessed as protein-compound complex at 10 uM relative to control | Homo sapiens | 1 | ALA3425442 | single protein format | Scientific Literature | |
5. | ALA3578859 | Binding | Displacement of [3H]ketanserin from human 5-HT2A receptor transfected in HEK293 cells by scintillation counting analysis | Homo sapiens | 8 | ALA3576771 | cell-based format | Scientific Literature | |
6. | ALA3579118 | Binding | Binding affinity to human 5HT2A receptor at 1 uM | Homo sapiens | 4 | ALA3576859 | single protein format | Scientific Literature | |
7. | ALA3583843 | Binding | Binding affinity to 5HT-2A receptor (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3580567 | single protein format | Scientific Literature | |
8. | ALA3584693 | Binding | Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in HEKT cell membranes by radioligand binding assay | Homo sapiens | 17 | ALA3580564 | cell-based format | Scientific Literature | |
9. | ALA3592649 | Binding | Displacement of [3H]ketanserin from human cloned 5HT2A receptor expressed in HEK293 cells at 1uM by scintillation counting analysis | Homo sapiens | 4 | ALA3588770 | cell-based format | Scientific Literature | |
10. | ALA3592665 | Functional | Agonist activity at human recombinant 5HT2A receptor expressed in HEK293 cells assessed as intracellular IP1 release at 1 uM by HTRF assay | Homo sapiens | 2 | ALA3588770 | cell-based format | Scientific Literature | |
11. | ALA3592666 | Functional | Antagonist activity at human recombinant 5HT2A receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced intracellular IP1 release at 1 uM by HTRF assay | Homo sapiens | 2 | ALA3588770 | cell-based format | Scientific Literature | |
12. | ALA3590821 | Binding | Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 cell membranes | Homo sapiens | 11 | ALA3588764 | cell-based format | Scientific Literature | |
13. | ALA3590934 | Binding | Binding affinity to 5-HT2A receptor (unknown origin) by PDSP assay | Homo sapiens | 20 | ALA3588775 | single protein format | Scientific Literature | |
14. | ALA3590937 | Binding | Partial agonist activity at human 5-HT2A receptor expressed in HEK293 cells preincubated for 1 hr at 37 degC followed by incubated for 15 mins at room temperature by IP-One assay | Homo sapiens | 6 | ALA3588775 | cell-based format | Scientific Literature | |
15. | ALA3590940 | Binding | Partial agonist activity at human 5-HT2A receptor expressed in HEK293 cells preincubated for 1 hr at 37 degC followed by incubated for 15 mins at room temperature by IP-One assay relative to 5-HT | Homo sapiens | 5 | ALA3588775 | cell-based format | Scientific Literature | |
16. | ALA3590942 | Functional | Partial agonist activity at human 5-HT2A receptor expressed in human tsA201 cells after 30 mins by inositol phosphate turnover assay | Homo sapiens | 1 | ALA3588775 | cell-based format | Scientific Literature | |
17. | ALA3590945 | Functional | Partial agonist activity at human 5-HT2A receptor expressed in human tsA201 cells after 30 mins by inositol phosphate turnover assay relative to 5-HT | Homo sapiens | 1 | ALA3588775 | cell-based format | Scientific Literature | |
18. | ALA3590947 | Binding | Displacement of [3H]-Ketanserin from human 5-HT2A receptor by PDSP assay | Homo sapiens | 1 | ALA3588775 | single protein format | Scientific Literature | |
19. | ALA3596072 | Binding | Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEKT cells membranes at 10 uM | Homo sapiens | 15 | ALA3593163 | cell-based format | Scientific Literature | |
20. | ALA3599950 | Binding | Displacement of [125I]DOI from 5HT2A receptor (unknown origin) | Homo sapiens | 7 | ALA3596172 | single protein format | Scientific Literature |