| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3069695 | A | Half life in 100% Rattus norvegicus (rat) whole blood assessed as conversion to 1-(4-Nitrobenzyl-3-{(bis(2-chloroethyl)amino)carbamoyl}pyridinium bromide at 10 x 10'-4 M by UV-spectrophotometric analysis | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 2. | ALA3068854 | A | Half life in 100% Rattus norvegicus (rat) whole blood assessed as conversion to 1-Benzyl-3-{(bis(2-chloroethyl)amino)carbamoyl}pyridinium bromide at 10 x 10'-4 M by UV-spectrophotometric analysis | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 3. | ALA3068858 | A | Half life in 100% Rattus norvegicus (rat) whole blood assessed as conversion to 1-Propyl-3-{(bis(2-chloroethyl)amino)carbamoyl}pyridinium bromide at 10 x 10'-4 M by UV-spectrophotometric analysis | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 4. | ALA3068862 | A | Half life in 100% Rattus norvegicus (rat) whole blood assessed as conversion to 1-Ethyl-3-{(bis(2-chloroethyl)amino)carbamoyl}-pyridinium iodide at 10 x 10'-4 M by UV-spectrophotometric analysis | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 5. | ALA3136560 | A | Protein binding in rat whole blood at 1 mg/kg, iv or 3 mg/kg, po by LC-MS/MS method | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA3292529 | F | Antiinflammatory activity in rat whole blood assessed as inhibition of LPS-induced TNFalpha production after 20 hrs by ELISA | Rattus norvegicus | 5 | tissue-based format | Scientific Literature | ||
| 7. | ALA3362640 | A | Half life in rat whole blood | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 8. | ALA3405050 | F | Inhibition of IL2 secretion in rat whole blood after 24 hrs by Rat IL-2 DuoSet assay | Rattus norvegicus | 3 | tissue-based format | Scientific Literature | ||
| 9. | ALA3539216 | A | Biodistribution in albino Wistar Hannover rat whole blood at 5 mg/kg, iv after 5 mins by liquid scintillation counting | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA3541616 | A | Retention time in rat whole blood in presence of 0.1% formic acid in water at 20 uM by LC-MS/MS method | Rattus norvegicus | 8 | tissue-based format | Scientific Literature | ||
| 11. | ALA3541618 | A | Retention time in rat whole blood in presence of 0.1% formic acid in acetonitrile at 20 uM by LC-MS/MS method | Rattus norvegicus | 7 | tissue-based format | Scientific Literature | ||
| 12. | ALA3541620 | A | Drug metabolism in rat whole blood assessed as [(S)-2-amino-5-(((R)-1-((carboxymethyl)amino)-3-((2-(3,3-dinitroazetidin-1-yl)-2-oxoethyl)thio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid] formation at 20 uM by LC-MS/MS method | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 13. | ALA3541622 | A | Drug metabolism in rat whole blood assessed as (R)-2-amino-3-((2-(3,3-dinitroazetidin-1-yl)-2-oxoethyl)thio)propanoic acid] formation at 20 uM by LC-MS/MS method | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 14. | ALA3541624 | A | Drug metabolism in rat whole blood assessed as [(S)-2-amino-5-(((R)-1-((carboxymethyl)amino)-3-((2-(3-nitroazetidin-1-yl)-2-oxoethyl)thio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid] formation at 20 uM by LC-MS/MS method | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 15. | ALA3541626 | A | Drug metabolism in rat whole blood assessed as [(R)-2-amino-3-((2-(3-nitroazetidin-1-yl)-2-oxoethyl)thio)propanoic acid] formation at 20 uM by LC-MS/MS method | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 16. | ALA3541628 | A | Drug metabolism in rat whole blood assessed as [(R)-2-(2-amino-3-((2-(3,3-dinitroazetidin-1-yl)-2-oxoethyl)thio)propanamido)acetic acid] formation at 20 uM by LC-MS/MS method | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 17. | ALA3541630 | A | Drug metabolism in rat whole blood assessed as [(S)-2-amino-5-(((R)-1-((carboxymethyl)amino)-1-oxo-3-((2-oxo-2-(3-oxoazetidin-1-yl)ethyl)thio)propan-2-yl)amino)-5-oxopentanoic acid] formation at 20 uM by LC-MS/MS method | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 18. | ALA3541632 | A | Drug metabolism in rat whole blood assessed as [(S)-2-amino-5-(((R)-1-((carboxymethyl)amino)-3-((2-(3-(hydroxyimino)azetidin-1-yl)-2-oxoethyl)thio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid] formation at 20 uM by LC-MS/MS method | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 19. | ALA3541634 | A | Drug metabolism in rat whole blood treated with 20 uM RRx-001 assessed as compound formation by LC-MS/MS method | Rattus norvegicus | 7 | tissue-based format | Scientific Literature | ||
| 20. | ALA3539455 | A | Drug metabolism in Sprague-Dawley rat whole blood assessed as BFBDS metabolite formation by HPLC analysis | Rattus norvegicus | 1 | tissue-based format | Scientific Literature |
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