| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3061922 | A | Half life in Homo sapiens (human) liver microsomes at 1 uM by LC/MS/MS analysis | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 2. | ALA3057246 | A | Half life in Homo sapiens (human) liver microsome at 1 uM | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 3. | ALA3095281 | A | Metabolic stability in human liver microsomes assessed as time when 50% of compound remains | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 4. | ALA3096354 | A | Clearance in human liver microsomes at 5 uM by LC-MS/MS analysis | Homo sapiens | 22 | assay format | Scientific Literature | ||
| 5. | ALA3096373 | A | Drug metabolism in human liver microsomes assessed as 3-(trifluoromethyl)-benzenesulfonamide level after 1 hr in presence of NADPH | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 6. | ALA3096375 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 10 uM after 1 hr in presence of NADPH | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 7. | ALA3097247 | A | Intrinsic clearance in human liver microsomes at 1 uM after 2 to 60 mins by LCMS analysis in absence of NADPH | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 8. | ALA3097248 | A | Intrinsic clearance in human liver microsomes at 1 uM after 2 to 60 mins by LCMS analysis in presence of NADPH | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 9. | ALA3095337 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA3096411 | A | Drug metabolism in human liver microsomes assessed as hydroxylation metabolite formation by LC-MS/MS analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA3096412 | A | Half life in human liver microsomes | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA3096413 | A | Metabolic stability in human liver microsomes assessed as compound remaining after 60 mins | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA3100966 | A | Metabolic stability in human liver microsomes assessed as glutathione adduct formation | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA3100967 | A | Metabolic stability in human liver microsomes assessed as oxidation | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA3100968 | A | Drug metabolism in human liver microsomes assessed as formation of 2-((R)-2-((S)-4-amino-4-carboxybutanamido)-3-(carboxymethylamino)-3-oxopropylthio)-6-(2,5-difluorobenzyl)-3-hydroxy-8-(2-oxo-1,2-dihydropyridin-3-yl)-3,6-dihydro-2H-furo[2,3-e]indole-7-carboxylic acid in presence of glutathione | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA3100969 | A | Drug metabolism in human liver microsomes assessed as formation of 6-(2,5-difluorobenzyl)-3-hydroxy-2-(methoxyamino)-8-(2-oxo-1,2-dihydropyridin-3-yl)-3,6-dihydro-2H-furo[2,3-e]indole-7-carboxylic acid in presence of NH2OCH3 | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA3100970 | A | Drug metabolism in human liver microsomes assessed as formation of 3-(2,5-Difluoro-benzyl)-1-(2-oxo-1,2-dihydro-pyridin-3-yl)-5b,6a-dihydro-3H-6,7-dioxa-3-aza-cyclopropa[b]-as-indacene-2-carboxylic acid | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 18. | ALA3100971 | A | Drug metabolism in human liver microsomes assessed as formation of 6-(2,5-difluorobenzyl)-2,3-dihydroxy-8-(2-oxo-1,2-dihydropyridin-3-yl)-3,6-dihydro-2H-furo[2,3-e]indole-7-carboxylic acid in presence of water | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA3100972 | A | Drug metabolism in human liver microsomes assessed as formation of 8-(1H-pyrrol-2-yl)-6H-furo[2,3-e]indole-7-carboxylic acid | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA3100989 | A | Metabolic stability of the compound in human liver microsomes assessed as compound remaining at 1 uM after 30 mins | Homo sapiens | 14 | assay format | Scientific Literature |
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