| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA660671 | B | Compound was evaluated for inhibitory activity against Trichoderma Chitinase | Trichoderma | 5 | single protein format | Scientific Literature | ||
| 2. | ALA661473 | B | Compound was evaluated for inhibitory activity against Trichoderma Chitinase in presence of allosamidin at the dose of 125 ug/mL | Trichoderma | 1 | single protein format | Scientific Literature | ||
| 3. | ALA661474 | B | Compound was evaluated for inhibitory activity against Trichoderma Chitinase in presence of allosamidin at the dose of 31 ug/mL | Trichoderma | 1 | single protein format | Scientific Literature | ||
| 4. | ALA661475 | B | Compound was evaluated for inhibitory activity against Trichoderma Chitinase in presence of allosamidin at the dose of 7.8 ug/mL | Trichoderma | 1 | single protein format | Scientific Literature | ||
| 5. | ALA875386 | B | Compound was evaluated for inhibitory activity against trichoderma chitinase in presence of allosamidin at the dose of 500 ug/mL | Trichoderma | 1 | single protein format | Scientific Literature | ||
| 6. | ALA5256815 | B | Inhibition of human CHIT1 using 4-methylumbelliferyl-beta-D-N,N',N''-triacetylchitotriose as substrate assessed as substrate hydrolysis at 50 uM preincubated with compound for 20 mins and measured immediately after substrate addition by fluorescence based assay relative to control | Homo sapiens | 22 | single protein format | Scientific Literature | ||
| 7. | ALA5256816 | B | Inhibition of human CHIT1 using 4-methylumbelliferyl-beta-D-N,N',N''-triacetylchitotriose as substrate assessed as substrate hydrolysis by measuring inhibition constant preincubated with compound for 20 mins and measured immediately after substrate addition by fluorescence based assay relative to control | Homo sapiens | 23 | single protein format | Scientific Literature | ||
| 8. | ALA5256818 | B | Inhibition of human CHIT1 using 4-methylumbelliferyl-beta-D-N,N',N''-triacetylchitotriose as substrate assessed as substrate hydrolysis at 10 uM preincubated with compound for 20 mins and measured immediately after substrate addition by fluorescence based assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4022941 | B | Inhibition of human recombinant full length C-terminal His-tagged chitotriosidase expressed in CHO-K1 cells using 4-methylumbelliferyl-beta-D-N,N',N\"\"-triacetylchitotrioside as substrate after 60 mins by fluorescence assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 10. | ALA4022945 | B | Inhibition of human recombinant full length C-terminal His-tagged chitotriosidase expressed in CHO-K1 cells using 4-methylumbelliferyl-beta-D-N,N',N\"\"-triacetylchitotrioside as substrate after 60 mins by Lineweaver-Burk plot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4312826 | B | Inhibition of full-length C-terminal his-tagged human CHIT1 expressed in CHOK1 cells assessed as reduction in chitinolytic activity using 4-methylumbelliferyl-beta-D-N,N',N\"-triacetylchitotrioside as substrate after 60 mins by fluorometric assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 12. | ALA4357675 | B | Binding affinity to human CHIT1 catalytic domain overexpressed in Pichia pastoris assessed by isothermal titration calorimetry | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4357676 | B | Binding affinity to human CHIT1 catalytic domain overexpressed in Pichia pastoris assessed as association constant by isothermal titration calorimetry | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA4357680 | B | Inhibition of human CHIT1 catalytic domain overexpressed in Pichia pastoris at 10 uM using 4MU-(GlcNAc)2 as substrate after 30 mins by fluorescence based microplate reader analysis | Homo sapiens | 23 | assay format | Scientific Literature | ||
| 15. | ALA4357688 | B | Inhibition of human CHIT1 catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by fluorescence based microplate reader analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 16. | ALA4357689 | B | Inhibition of human CHIT1 catalytic domain overexpressed in Pichia pastoris at 50 uM using 4MU-(GlcNAc)2 as substrate after 30 mins by fluorescence based microplate reader analysis relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4619012 | B | Inhibition of human CHIT1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4619015 | B | Inhibition of full length recombinant C-terminal His-taged human CHIT1 expressed in CHOK1 cells assessed as reduction in chitinolytic activity using 4-methylumbelliferyl-beta-D-N,N',N''-diacetylchitotrioside as substrate incubated for 60 mins under shaking condition by microplate fluorometry analysis | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 19. | ALA4704014 | B | Inhibition of full-length C-terminal his-tagged human recombinant CHIT1 catalytic domain (1 to 386 residues) expressed in HEK293F cells assessed as reduction in chitinolytic activity using 4-methylumbelliferyl-beta-D-N,N',N"-triacetylchitotrioside as substrate after 60 mins by fluorometric assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 20. | ALA4722990 | A | Inhibition of human chitinase1 incubated for 70 mins using 4MU-NAG2 as substrate by fluorescence method | Homo sapiens | 1 | single protein format | Scientific Literature |
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