# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3057243 | A | Prodrug conversion in male Rattus norvegicus (rat) liver cytosol assessed as (S)-3-(1-(benzo[d][1,3]dioxol-5-yl)-2-(2-methoxy-4-methylphenylsulfonamido)-2-oxoethyl)-1-methyl-1H-indole-6-carboxylic acid formation | Rattus norvegicus | 1 | ALA3045872 | tissue-based format | Scientific Literature | |
2. | ALA3381504 | A | Prodrug conversion in rat liver cytosol assessed as half life for metformin formation at 100 uM in presence of a NADPH-regenerating system by HPLC method | Rattus norvegicus | 1 | ALA3351963 | tissue-based format | Scientific Literature | |
3. | ALA3541058 | A | Drug metabolism in rat liver cytosol assessed as sulfate metabolite formation by Michaelis-Menten equation in presence of NADPH | Rattus norvegicus | 2 | ALA3525936 | assay format | Scientific Literature | |
4. | ALA3534819 | A | Drug level in rat liver cytosol assessed as compound formation treated with 2 uM [14C]brivanib alaninate after 60 mins by LC/MS method in presence of 1 mM NADPH | Rattus norvegicus | 1 | ALA3525936 | tissue-based format | Scientific Literature | |
5. | ALA3534825 | A | Drug level in rat liver cytosol assessed as compound formation treated with 2 uM [14C]brivanib alaninate after 60 mins by LC/MS method in presence of 1 mM NAD+ | Rattus norvegicus | 1 | ALA3525936 | tissue-based format | Scientific Literature | |
6. | ALA3534828 | A | Drug level in rat liver cytosol assessed as compound formation treated with 10 uM (S)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-yloxy)propan-2-ol after 60 mins by LC/MS method in presence of 1 mM NADPH | Rattus norvegicus | 1 | ALA3525936 | tissue-based format | Scientific Literature |