# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2382484 | B | Inhibition of PARP6 (unknown origin) | Homo sapiens | 2 | ALA2380224 | single protein format | Scientific Literature | |
2. | ALA2382491 | B | Inhibition of PARP6 (unknown origin) at 10 uM relative to control | Homo sapiens | 2 | ALA2380224 | single protein format | Scientific Literature | |
3. | ALA2384338 | B | Inhibition of PARP6 (unknown origin) using histone as substrate after 1 hr by luminescence assay | Homo sapiens | 1 | ALA2380263 | single protein format | Scientific Literature | |
4. | ALA3242398 | B | Inhibition of recombinant human PARP-6 at 10 uM relative to control | Homo sapiens | 1 | ALA3232733 | single protein format | Scientific Literature | |
5. | ALA3382573 | B | Inhibition of human recombinant PARP6 at 10 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | ALA3351316 | single protein format | Scientific Literature | |
6. | ALA3382583 | B | Inhibition of human recombinant PARP6 at 100 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | ALA3351316 | single protein format | Scientific Literature | |
7. | ALA3743853 | B | Inhibition of full length human PARP6 expressed in a Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidin-horseradish peroxidase-based luminescence assay | Homo sapiens | 3 | ALA3739394 | cell-based format | Scientific Literature | |
8. | ALA4322265 | B | Inhibition of N-terminal GST-tagged recombinant human full length PARP6 expressed in Baculovirus infected Sf9 cells using biotinylated substrate after 1 hr by chemiluminescence method | Homo sapiens | 1 | ALA4321794 | cell-based format | Scientific Literature | |
9. | ALA4678528 | B | Inhibition of PARP-6 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assay | Homo sapiens | 1 | ALA4673340 | single protein format | Scientific Literature | |
10. | ALA4701308 | B | Inhibition of N-terminal GST tagged full length human PARP6 expressed in baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ribosylation using histone as substrate at 10 uM incubated for 1 hr in presence of biotinylated NAD+ and activated DNA by chemiluminescence based microplate reader assay relative to control | Homo sapiens | 2 | ALA4699460 | cell-based format | Scientific Literature | |
11. | ALA5108308 | B | Inhibition of N-terminal His-tagged full length human PARP6 expressed in Escherichia coli BL21 (DE3) at 10 uM preincubated with 6-a-NAD+ for 5 to 10 mins followed by enzyme addition and measured after 60 mins using NAD+ as substrate byHRP based chemiluminescence assay | Homo sapiens | 6 | ALA5107944 | assay format | Scientific Literature | |
12. | ALA5124501 | B | Inhibition of PARP6 (unknown origin) | Homo sapiens | 1 | ALA5120882 | single protein format | Scientific Literature | |
13. | ALA5228292 | B | Inhibition of N-terminal GST-tagged human recombinant PARP6 (1 to 630 residues) expressed in Sf9 insect cells by chemiluminescence assay | Homo sapiens | 1 | ALA5226325 | cell-based format | Scientific Literature |