| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2382490 | B | Inhibition of PARP11 (unknown origin) at 10 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 2. | ALA3242402 | B | Inhibition of recombinant human PARP-11 at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA3382577 | B | Inhibition of human recombinant PARP11 at 10 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA3382587 | B | Inhibition of human recombinant PARP11 at 100 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4012887 | B | Binding affinity to PARP11 in human Jurkat cell extract after 45 mins by mass spectrometric analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 6. | ALA4311837 | B | Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by chemifluorescence assay | Homo sapiens | 25 | assay format | Scientific Literature | ||
| 7. | ALA4322269 | B | Inhibition of human N-terminal GST-tagged PARP11 (8 to 338 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated substrate by chemiluminescence method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4678524 | B | Inhibition of PARP-11 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4701311 | B | Inhibition of N-terminal GST tagged human PARP11 (8 to 338 residues) expressed in baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ribosylation using histone as substrate at 10 uM incubated for 1 hr in presence of biotinylated NAD+ and activated DNA by chemiluminescence based microplate reader assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA5108302 | B | Inhibition of N-terminal His-tagged full length human PARP11 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins followed by enzyme addition and measured after 60 mins using NAD+ as substrate byHRP based chemiluminescence assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA5108312 | B | Inhibition of N-terminal His-tagged full length human PARP11 expressed in Escherichia coli BL21 (DE3) at 10 uM preincubated with 6-a-NAD+ for 5 to 10 mins followed by enzyme addition and measured after 60 mins using NAD+ as substrate byHRP based chemiluminescence assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 12. | ALA5123575 | B | Inhibition of human full length GFP-tagged PARP11 in human HeLa cells incubated for 3 hrs by chemiluminescence based analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5124489 | B | Inhibition of PARP11 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 14. | ALA5152049 | B | Binding affinity to PARP11 (unknown origin) assessed as apparent dissociation constant | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 15. | ALA5228296 | B | Inhibition of N-terminal GST-tagged/C-terminal 6xHis-tagged human recombinant PARP11 (8 to 338 residues) expressed in Sf9 insect cells by chemiluminescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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