# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA779290 | F | In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slices | Rattus norvegicus | 2 | ALA1128393 | assay format | Scientific Literature | |
2. | ALA779291 | F | In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slices | Rattus norvegicus | 2 | ALA1128393 | assay format | Scientific Literature | |
3. | ALA795307 | F | In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slices | Rattus norvegicus | 2 | ALA1128393 | assay format | Scientific Literature | |
4. | ALA795453 | F | In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slices | Rattus norvegicus | 1 | ALA1128393 | assay format | Scientific Literature | |
5. | ALA795454 | F | In vitro inhibition of aldosterone production in rat adrenal tissue | Rattus norvegicus | 1 | ALA1125660 | tissue-based format | Scientific Literature | |
6. | ALA794467 | F | In vitro inhibition of aldosterone production in rat adrenal tissue | Rattus norvegicus | 1 | ALA1125660 | tissue-based format | Scientific Literature | |
7. | ALA847044 | F | In vitro inhibition of aldosterone production in rat adrenal tissue | Rattus norvegicus | 1 | ALA1125660 | tissue-based format | Scientific Literature | |
8. | ALA844572 | F | In vitro inhibition of aldosterone production in rat adrenal tissue | Rattus norvegicus | 1 | ALA1125660 | tissue-based format | Scientific Literature | |
9. | ALA3101039 | B | Inhibition of rat recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assay | Rattus norvegicus | 4 | ALA3098017 | cell-based format | Scientific Literature | |
10. | ALA3366448 | B | Inhibition of aldosterone synthase in rat adrenal assessed as decrease in aldosterone level at 100 uM | Rattus norvegicus | 1 | ALA3352462 | assay format | Scientific Literature | |
11. | ALA3366796 | B | Inhibition of aldosterone synthase in rat adrenal assessed as decrease in 18-OH-corticosterone level at 100 uM | Rattus norvegicus | 1 | ALA3352462 | assay format | Scientific Literature | |
12. | ALA3399808 | B | Inhibition of rat CYP11B2 using [3H]-11-deoxycorticosterone as substrate at 2 uM incubated for 1 hr prior to substrate addition measured after 7 hrs by HPLC analysis | Rattus norvegicus | 5 | ALA3396957 | single protein format | Scientific Literature | |
13. | ALA3399837 | B | Inhibition of rat CYP11B2 using [3H]-11-deoxycorticosterone as substrate at 0.5 uM incubated for 1 hr prior to substrate addition measured after 7 hrs by HPLC analysis | Rattus norvegicus | 1 | ALA3396957 | single protein format | Scientific Literature | |
14. | ALA3583963 | B | Inhibition of rat CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assay | Rattus norvegicus | 5 | ALA3580617 | cell-based format | Scientific Literature | |
15. | ALA3624752 | B | Inhibition of rat CYP11B2 expressed in renal leiomyoblastoma cells at 500 nM relative to control | Rattus norvegicus | 1 | ALA3621059 | cell-based format | Scientific Literature | |
16. | ALA3625365 | B | Inhibition of rat CYP11B2 expressed in V79 cells assessed as aldosterone level after 3 hrs by HTRF assay in presence of 500 nM 11-deoxycorticosterone | Rattus norvegicus | 3 | ALA3621164 | cell-based format | Scientific Literature | |
17. | ALA3750679 | B | Inhibition of recombinant rat CYP11B2 using 11-deoxycorticosterone as substrate after 2 hrs by scintillation proximity assay | Rattus norvegicus | 6 | ALA3745671 | single protein format | Scientific Literature | |
18. | ALA4012486 | B | Inhibition of rat CYP11B2 | Rattus norvegicus | 1 | ALA4011612 | single protein format | Scientific Literature | |
19. | ALA4029975 | B | Inhibition of rat CYP11B2-1F4 expressed in Chinese hamster V79 cells using 11-deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition measured for 3 hrs by HTRF assay | Rattus norvegicus | 5 | ALA4028827 | cell-based format | Scientific Literature |