# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1048603 | F | Agonist activity at LXRbeta in mouse J774 cells assessed as upregulation of ABCA1 mRNA expression | Mus musculus | 11 | cell-based format | Scientific Literature | ||
2. | ALA1048604 | F | Agonist activity at LXRbeta in mouse J774 cells assessed as upregulation of ABCA1 mRNA expression relative to T0901317 | Mus musculus | 10 | cell-based format | Scientific Literature | ||
3. | ALA2422716 | B | Agonist activity at LXRbeta in mouse BV2 cells assessed as degradation of intracellular soluble amyloid beta42 at 0.1 uM preincubated for 18 hrs followed by soluble amyloid beta42 addition measured after 24 hrs by ELISA relative to vehicle-treated control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
4. | ALA2422717 | B | Agonist activity at LXRbeta in mouse BV2 cells assessed as degradation of intracellular soluble amyloid beta42 at 0.01 uM preincubated for 18 hrs followed by soluble amyloid beta42 addition measured after 24 hrs by ELISA relative to vehicle-treated control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA2422718 | B | Agonist activity at LXRbeta in mouse BV2 cells assessed as degradation of intracellular amyloid beta42 preincubated for 18 hrs followed by soluble amyloid beta42 addition measured after 24 hrs by ELISA | Mus musculus | 2 | cell-based format | Scientific Literature | ||
6. | ALA2422719 | B | Agonist activity at LXRbeta in mouse BV2 cells assessed as degradation of intracellular soluble amyloid beta42 at 1 uM preincubated for 18 hrs followed by soluble amyloid beta42 addition measured after 24 hrs by ELISA relative to vehicle-treated control | Mus musculus | 13 | cell-based format | Scientific Literature | ||
7. | ALA2422720 | B | Agonist activity at LXRbeta in mouse BV2 cells assessed as upregulation of apoE protein expression at 10 uM after 48 hrs by Western blot analysis relative to vehicle-treated control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
8. | ALA2422721 | B | Agonist activity at LXRbeta in mouse BV2 cells assessed as upregulation of apoE protein expression at 1 uM after 48 hrs by Western blot analysis relative to vehicle-treated control | Mus musculus | 3 | cell-based format | Scientific Literature | ||
9. | ALA2422722 | B | Agonist activity at LXRbeta in mouse BV2 cells assessed as upregulation of apoE protein expression at 0.1 uM after 48 hrs by Western blot analysis relative to vehicle-treated control | Mus musculus | 3 | cell-based format | Scientific Literature | ||
10. | ALA2422723 | B | Agonist activity at LXRbeta in mouse BV2 cells assessed as upregulation of ABCA1 protein expression after 12 to 48 hrs by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
11. | ALA2422724 | B | Agonist activity at LXRbeta in mouse BV2 cells assessed as upregulation of ABCA1 protein expression at 1 uM after 12 to 48 hrs by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
12. | ALA2422725 | B | Agonist activity at LXRbeta in mouse RAW264.7 cells assessed as upregulation of ABCA1 protein expression after 18 to 48 hrs by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
13. | ALA2422726 | B | Agonist activity at LXRbeta in mouse RAW264.7 cells assessed as upregulation of ABCA1 protein expression at 1 uM after 18 to 48 hrs by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
14. | ALA2421021 | B | Agonist activity at LXRbeta in mouse RAW264.7 cells assessed as induction of ABCA1 promoter activation after 24 hrs by Dual-Glo luciferase reporter gene assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
15. | ALA2421022 | B | Agonist activity at LXRbeta in mouse RAW264.7 cells assessed as induction of ABCA1 promoter activation at 1 uM after 24 hrs by Dual-Glo luciferase reporter gene assay relative to vehicle-treated control | Mus musculus | 45 | cell-based format | Scientific Literature | ||
16. | ALA4188160 | B | Agonist activity at mouse LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
17. | ALA4188161 | B | Agonist activity at mouse LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene assay relative to T0901317 | Mus musculus | 4 | cell-based format | Scientific Literature | ||
18. | ALA5121380 | B | Agonist activity at mouse LXRbeta | Mus musculus | 2 | single protein format | Scientific Literature |