| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2422302 | B | Inhibition of human recombinant TRPC6 expressed in HEK293 cells assessed as 1-oleoyl-2-acetyl-glycerol-stimulated current at 0.01 to 0.03 uM by whole cell electrophysiology assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA2422303 | B | Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 3. | ALA3997752 | B | Inhibition of TRPC6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA4122824 | B | Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 5. | ALA4158456 | B | Inhibition of TRPC6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4377082 | B | Inhibition of YFP-tagged human TRPC6 expressed in thapsigargin treated HEK293 cells assessed as reduction in amix-induced calcium level by fluo-4 dye based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4377103 | B | Inhibition of human TRPC6 expressed in thapsigargin pretreated HEK293 cells assessed as reduction in GPCR-induced calcium entry by fluo-4/AM dye based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4377104 | B | Inhibition of human TRPC6 expressed in HEK293 cells assessed as reduction in OAG-induced calcium influx preincubated for 2 mins followed by OAG stimulation by fluo-4/AM dye based FLIPR assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4377107 | B | Inhibition of human TRPC6 expressed in HEK293 cells assessed as reduction in OAG-induced calcium influx after 10 mins by fluo-4/AM dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4377110 | B | Inhibition of human TRPC6 expressed in HEK293 cells assessed as reduction in TRPC6-induced current by Whole-cell patch-clamp | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4410993 | B | Inhibition of OAG-activated human TRPC6 channel expressed in HEK293 cells by Q-patch clamp assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4725099 | B | Inhibition of human TRPC6 channel transfected in HEK293 cells assessed as intracellular calcium level by FLIPR assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 13. | ALA4828447 | B | Antagonist activity at human TRPC6 at <= 30 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4885662 | B | TRP selectivity screen (TRPC6) | Homo sapiens | 2 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 15. | ALA5055792 | B | Inhibition of human TRPC6 expressed in HEK293F cells assessed as inhibition of carbachol-induced calcium response up to 20 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5145641 | B | Inhibition of TRPC6 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of OAG-evoked Ca2+ entry by measuring reduction in intracellular Ca2+ level by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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