| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2422304 | B | Inhibition of human recombinant TRPC3 expressed in HEK293 cells assessed as 1-oleoyl-2-acetyl-glycerol-stimulated current at 0.01 to 0.03 uM by whole cell electrophysiology assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA2422305 | B | Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 3. | ALA3361960 | B | Blocking of human TRPC3 expressed in HEK cells by MSRII FLIPR/summary (Abse5) assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3361961 | B | Induction of human TRPC3 opening expressed in HEK cells by MSRII FLIPR/summary (Abse5) assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3997751 | B | Inhibition of TRPC3 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4015184 | B | Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 mM Ca2+ by FLIPR membrane potential dye-based fluorescence assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4015185 | B | Agonist activity at human TRPC3 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins by Fluo-8-AM dye based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4015212 | B | Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 2 mM Ca2+ by FLIPR membrane potential dye-based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4015213 | B | Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of channel current at 10 uM measured for 2.5 mins in presence of 0.5 mM Ca2+ by whole cell patch-clamp method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4158453 | B | Inhibition of TRPC3 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4377058 | B | Inhibition of human TRPC3 expressed in HEK293 cells assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 12. | ALA4377081 | B | Inhibition of YFP-tagged human TRPC3 expressed in thapsigargin treated HEK293 cells assessed as reduction in amix-induced calcium level by fluo-4 dye based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4377098 | B | Inhibition of TRPC3 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4377100 | B | Inhibition of YFP-tagged TRPC3 (unknown origin) expressed in HEK293 cells assessed as reduction carbhocol-induced receptor operated Calcium influx after 5 mins by fura-2-AM dye based assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA4377108 | B | Inhibition of human TRPC3 expressed in CHO cells assessed as reduction in OAG-induced calcium influx after 10 mins by fluo-4/AM dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4411001 | B | Inhibition of TRPC3 channel (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA4714753 | B | Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current at 10 uM in absence of extracellular calcium by whole cell patch-clamp method relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 18. | ALA4714754 | B | Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current in absence of extracellular calcium by whole cell patch-clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4714755 | B | Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current in presence of 2 mM extracellular calcium by whole cell patch-clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4714756 | B | Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of OAG-induced current at 0.001 to 10 uM by whole cell patch-clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature |
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