| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2422850 | B | Inhibition of Bacillus subtilis SU570 GFP-fused FtsZ assessed as perturbation of Z-ring formation at 12 uM after 60 mins by fluorescence microscopic analysis | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 2. | ALA2422851 | B | Inhibition of Bacillus subtilis FtsZ GTPase activity assessed as production of inorganic phosphate measured up to 60 mins by malachite green-phosphomolybdate colorimetric assay | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2423036 | B | Displacement of [3H]-GTP from Bacillus subtilis FtsZ assessed as equilibrium association constant by scintillation counting assay | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 4. | ALA2423037 | B | Displacement of mant-GTP from Bacillus subtilis FtsZ by fluorescence anisotropy analysis | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 5. | ALA2423038 | B | Displacement of mant-GTP from Bacillus subtilis FtsZ assessed as equilibrium association constant by fluorescence anisotropy analysis | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4121904 | B | Inhibition of FtsZ in penicillin-susceptible Bacillus subtilis ATCC 9372 assessed as increase in length of bacteria at 8 ug/ml after 5 hrs by phase-contrast light microscopic method | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4121906 | B | Inhibition of FtsZ in penicillin-susceptible Bacillus subtilis ATCC 9372 assessed as increase in length of bacteria at 0.125 ug/ml after 5 hrs by phase-contrast light microscopic method | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4121908 | B | Inhibition of penicillin-susceptible Bacillus subtilis ATCC 9372 N-terminal His6-tagged FtsZ expressed in Escherichia coli BL21 (DE3) cells by fluorescence spectrophotometer-based light scattering assay | Bacillus subtilis | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4121909 | B | Inhibition of penicillin-susceptible Bacillus subtilis ATCC 9372 N-terminal His6-tagged FtsZ expressed in Escherichia coli BL21 (DE3) cells at 10 ug/ml by fluorescence spectrophotometer-based light scattering assay | Bacillus subtilis | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4188576 | B | Inhibition of FtsZ in Bacillus subtilis ATCC 9372 assessed as filamentation at 1 ug/ml | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4188577 | B | Inhibition of FtsZ in Bacillus subtilis ATCC 9372 assessed as filamentation | Bacillus subtilis | 5 | single protein format | Scientific Literature | ||
| 12. | ALA4428180 | B | Inhibition of Bacillus subtilis FtsZ assessed as reduction in GTPase activity by malachite green assay | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4838263 | B | Induction of Bacillus subtilis FtsZ polymerization by fluorescence spectrophotometry | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4838264 | B | Induction of Bacillus subtilis FtsZ polymerization assessed as formation of bundling of FtsZ protofilaments at 10 ug/ml after 20 mins by transmission electron microscopic analysis | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4838271 | B | Inhibition of FtsZ in Bacillus subtilis assessed as disruption of Z ring formation | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 16. | ALA5034076 | B | Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysis | Bacillus subtilis | 18 | single protein format | Scientific Literature | ||
| 17. | ALA5034086 | B | Inhibition of GFP-tagged FtsZ in Bacillus subtilis SU570 assessed as induction of irregular shaped z-ring formation at 0.2 uM incubated for 1.5 hrs | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 18. | ALA5034087 | B | Inhibition of GFP-tagged FtsZ in Bacillus subtilis SU570 assessed as delocalization into punctate foci at 0.2 uM incubated for 1.5 hrs | Bacillus subtilis | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5034088 | B | Competitive binding affinity to Bacillus subtilis FtsZ at 10 uM in presence of PC190723 by fluorescence anisotropy analysis | Bacillus subtilis | 5 | single protein format | Scientific Literature | ||
| 20. | ALA5034089 | B | Induction of Bacillus subtilis FtsZ polymerization at 0.1 mM measured after 5 to 10 mins by fluorescence anisotropy analysis | Bacillus subtilis | 1 | single protein format | Scientific Literature |
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