| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2427485 | B | Antagonist activity at Pseudomonas aeruginosa PA14 PqsR assessed as reduction of pyocyanin level by UHPLC-MS/MS analysis | Pseudomonas aeruginosa PA14 | 3 | ALA2424512 | single protein format | Scientific Literature | |
| 2. | ALA2427486 | B | Antagonist activity at Pseudomonas aeruginosa PA14 PqsR assessed as reduction of pyocyanin level at 250 uM by UHPLC-MS/MS analysis | Pseudomonas aeruginosa PA14 | 3 | ALA2424512 | single protein format | Scientific Literature | |
| 3. | ALA2427487 | B | Antagonist activity at PqsH deficient Pseudomonas aeruginosa PA14 PqsR assessed as reduction of HQNO level at 250 uM by UHPLC-MS/MS analysis | Pseudomonas aeruginosa PA14 | 1 | ALA2424512 | single protein format | Scientific Literature | |
| 4. | ALA2427488 | B | Antagonist activity at wild type Pseudomonas aeruginosa PA14 PqsR assessed as reduction of extracellular PQS level by UHPLC-MS/MS analysis | Pseudomonas aeruginosa PA14 | 1 | ALA2424512 | single protein format | Scientific Literature | |
| 5. | ALA2427489 | B | Antagonist activity at PqsH deficient Pseudomonas aeruginosa PA14 PqsR assessed as reduction of extracellular HHQ level at 250 uM by UHPLC-MS/MS analysis | Pseudomonas aeruginosa PA14 | 1 | ALA2424512 | single protein format | Scientific Literature | |
| 6. | ALA2427490 | B | Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in pqs gene-deficient Pseudomonas aeruginosa PA14 by beta-galactosidase reporter gene assay | Pseudomonas aeruginosa PA14 | 1 | ALA2424512 | assay format | Scientific Literature | |
| 7. | ALA2427491 | B | Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activation by beta-galactosidase reporter gene assay | Pseudomonas aeruginosa PA14 | 7 | ALA2424512 | assay format | Scientific Literature | |
| 8. | ALA2427492 | B | Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activation at 100 uM by beta-galactosidase reporter gene assay relative to control | Pseudomonas aeruginosa PA14 | 25 | ALA2424512 | assay format | Scientific Literature | |
| 9. | ALA2427493 | B | Agonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha at 50 nM by beta-galactosidase reporter gene assay relative to control | Pseudomonas aeruginosa PA14 | 1 | ALA2424512 | assay format | Scientific Literature | |
| 10. | ALA2427494 | B | Agonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha at 100 uM by beta-galactosidase reporter gene assay relative to PQS | Pseudomonas aeruginosa PA14 | 25 | ALA2424512 | assay format | Scientific Literature | |
| 11. | ALA2427495 | B | Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titration calorimetry | Pseudomonas aeruginosa PA14 | 11 | ALA2424512 | assay format | Scientific Literature | |
| 12. | ALA2427496 | B | Competitive binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) at 1 to 81 uM by surface plasmon resonance spectroscopic analysis in presence of PQS | Pseudomonas aeruginosa PA14 | 2 | ALA2424512 | assay format | Scientific Literature | |
| 13. | ALA2427497 | B | Competitive binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) at 0.11 to 9 uM by surface plasmon resonance spectroscopic analysis in presence of PQS | Pseudomonas aeruginosa PA14 | 2 | ALA2424512 | assay format | Scientific Literature | |
| 14. | ALA2428111 | B | Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonance spectroscopic analysis | Pseudomonas aeruginosa PA14 | 7 | ALA2424512 | assay format | Scientific Literature | |
| 15. | ALA4315943 | B | Inhibition of Pseudomonas aeruginosa PAO1 PqsR assessed as reduction in pyocyanin production level at 10 uM measured after 10 mins by spectrometry based analysis | Pseudomonas aeruginosa PAO1 | 3 | ALA4312019 | single protein format | Scientific Literature | |
| 16. | ALA4315944 | B | Inhibition of Pseudomonas aeruginosa PAO1 PqsR assessed as increase in pyocyanin production level at 10 uM measured after 10 mins by spectrometry based analysis relative to control | Pseudomonas aeruginosa PAO1 | 3 | ALA4312019 | single protein format | Scientific Literature | |
| 17. | ALA4315946 | B | Inhibition of Pseudomonas aeruginosa PA14 PqsR transfected with pAW1-GFP at 10 uM measured after 12 hrs by fluorescence based microtiter plate reader method | Pseudomonas aeruginosa PA14 | 2 | ALA4312019 | assay format | Scientific Literature | |
| 18. | ALA4315990 | B | Inhibition of Pseudomonas aeruginosa PA14 PqsR transfected with pAW1-GFP at 10 uM measured after 12 hrs by fluorescence based microtiter plate reader method relative to control | Pseudomonas aeruginosa PA14 | 9 | ALA4312019 | assay format | Scientific Literature | |
| 19. | ALA4315998 | B | Inhibition of Pseudomonas aeruginosa PqsR at 5 uM relative to control | Pseudomonas aeruginosa | 1 | ALA4312019 | single protein format | Scientific Literature | |
| 20. | ALA4348586 | B | Antagonist activity at His6 -tagged Pseudomonas aeruginosa PqsR CBD domain expressed in Escherichia coli Rosetta 2 (DE3) | Pseudomonas aeruginosa | 3 | ALA4346692 | assay format | Scientific Literature |
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