| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA957239 | B | Inhibition of Staphylococcus aureus DNA gyrase gyrA S84L mutant supercoiling activity assessed as effect on conversion of relaxed pBR322 DNA to supercoiled form | Staphylococcus aureus | 5 | ALA1157373 | assay format | Scientific Literature | |
| 2. | ALA1066707 | B | Inhibition of Staphylococcus aureus DNA gyrase Ser84Leu mutant | Staphylococcus aureus | 6 | ALA1152592 | assay format | Scientific Literature | |
| 3. | ALA1281217 | B | Activity at Staphylococcus aureus wild-type GyrA S84L mutant | Staphylococcus aureus | 4 | ALA1275434 | assay format | Scientific Literature | |
| 4. | ALA1775520 | B | Inhibition of Staphylococcus aureus DNA gyrase Ser84Leu mutant assessed as inhibition of supercoiling of pBR322 DNA after 60 min by gel electrophoresis assay | Staphylococcus aureus | 7 | ALA1772978 | assay format | Scientific Literature | |
| 5. | ALA1775522 | B | Ratio of ciprofloxacin IC50 to compound IC50 for Staphylococcus aureus DNA gyrase Ser84Leu mutant | Staphylococcus aureus | 2 | ALA1772978 | assay format | Scientific Literature | |
| 6. | ALA2384766 | B | Inhibition of Staphylococcus aureus DNA gyrase D83N mutant | Staphylococcus aureus | 1 | ALA2380208 | assay format | Scientific Literature | |
| 7. | ALA2384767 | B | Inhibition of Staphylococcus aureus DNA gyrase M121K mutant | Staphylococcus aureus | 1 | ALA2380208 | assay format | Scientific Literature | |
| 8. | ALA2427058 | B | Inhibition of NXL-101-resistant Staphylococcus aureus DNA gyrase D83N mutant assessed as pBR322 supercoiling after 1 hr | Staphylococcus aureus | 5 | ALA2424615 | assay format | Scientific Literature | |
| 9. | ALA2427059 | B | Inhibition of quinolone-resistant Staphylococcus aureus A-798 DNA gyrase S84L mutant assessed as pBR322 supercoiling after 1 hr | Staphylococcus aureus | 5 | ALA2424615 | assay format | Scientific Literature | |
| 10. | ALA3879356 | B | Inhibition of Staphylococcus aureus DNA gyrase A expressed in Escherichia coli BL21(DE3) using relaxed pBR322 DNA as substrate incubated for 1 hr by bromophenol blue dye based agarose gel electrophoresis method | Staphylococcus aureus | 9 | ALA3877314 | assay format | Scientific Literature | |
| 11. | ALA4155174 | B | Inhibition of Staphylococcus aureus DNA gyrase subunit A supercoiling activity using relaxed pBR322 DNA as substrate after 60 mins by agarose gel electrophoresis | Staphylococcus aureus | 7 | ALA4152270 | single protein format | Scientific Literature | |
| 12. | ALA4374973 | B | Inhibition of Staphylococcus aureus DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA measured after 60 mins by electrophoresis method | Staphylococcus aureus | 1 | ALA4373693 | single protein format | Scientific Literature | |
| 13. | ALA4374980 | B | Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromide staining based gel electrophoresis method | Staphylococcus aureus | 40 | ALA4373693 | single protein format | Scientific Literature | |
| 14. | ALA4426540 | B | Inhibition of FQ-resistant Staphylococcus aureus GyrA S84L mutant assessed as compound concentration causing 50% induction of cleavage of covalently closed DNA substrate | Staphylococcus aureus | 3 | ALA4425125 | single protein format | Scientific Literature |
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