| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2429072 | B | Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assay | Homo sapiens | 56 | single protein format | Scientific Literature | ||
| 2. | ALA3136681 | B | Inhibition of 53BP1 (1485 to 1611) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay | Homo sapiens | 25 | assay format | Scientific Literature | ||
| 3. | ALA3222543 | B | Effect on GST-fused 53BP1 Tudor domain (unknown origin)/biotinylated H4K20Me1 peptide interaction assessed as binding of 53BP1 to H4K20Me1 at 5 uM by pull down assay based western blot analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 4. | ALA3222544 | B | Effect on GST-fused 53BP1 Tudor domain (unknown origin)/biotinylated H4K20Me1 peptide interaction assessed as binding of 53BP1 to H4K20Me1 at 25 uM by pull down assay based western blot analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 5. | ALA4138804 | B | Inhibition of 53BP1 methyllysine binding domain (unknown origin) after 30 mins by AlphaScreen assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA4138805 | B | Binding affinity to 53BP1 methyllysine binding domain (unknown origin) by ITC method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4138806 | B | Competitive displacement of p53K382me2 from His-tagged 53BP1 tandem Tudor domain (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4194972 | B | Binding affinity to 6His-tagged and human 53BP1 tandem TUDOR domain (1488 to 1611 residues) expressed in Escherichia coli BL21(DE3)-T1R by ITC method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA4377339 | B | Binding affinity to 53BP1 (unknown origin) assessed as induction of thermal shifts at 200 uM measured for 25 mins by SYPRO orange dye thermal shift assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4689468 | B | Inhibition of recombinant human N-terminal His6-tagged 53BP1 TTD (1484 to1603 residues) expressed in Escherichia coli BL21 (DE3) cells using Biotin-H4K2Ome2 as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by AlphaScreen assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 11. | ALA4689469 | B | Binding affinity to recombinant human N-terminal His6-tagged lysine dye- labeled 53BP1 TTD (1484 to1603 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 10 mins by MST assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4689470 | B | Binding affinity to recombinant human N-terminal His6-tagged 53BP1 TTD (1484 to1603 residues) expressed in Escherichia coli BL21 (DE3) cells by SPR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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