| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2433126 | B | Inhibition of human ARTD12 (489 to 684) using NAD+ as substrate at 1 uM by fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA3242403 | B | Inhibition of recombinant human PARP-12 at 10 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 3. | ALA3382578 | B | Inhibition of human recombinant PARP12 at 10 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA3382588 | B | Inhibition of human recombinant PARP12 at 100 uM incubated for 1 hr using using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA3757407 | B | Inhibition of human ARTD12 by fluorescence analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 6. | ALA3995369 | B | Inhibition of recombinant human His6-tagged PARP12 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 7. | ALA4003515 | B | Inhibition of PARP12 (unknown origin) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 8. | ALA4022068 | B | Inhibition of His6-tagged PARP12 (unknown origin) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4032833 | B | Inhibition of human PARP12 using NAD+ as substrate by fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4272750 | B | Inhibition of N-terminal His-tagged thioredoxin-fused human ARTD12 (469 to 701 residues) expressed in Escherichia coli Rosetta2 (DE3) after 20 hrs in presence of NAD+ | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 11. | ALA4311849 | B | Inhibition of GFP-tagged human PARP12 expressed in HEK293T cells assessed as reduction in auto-MARylation after 60 mins in presence of 6-a-NAD+ by chemiluminescent immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4322270 | B | Inhibition of human N-terminal His/GST-tagged PARP12 (500 to 701 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated substrate by chemiluminescence method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4380688 | B | Inhibition of PARP12 (unknown origin) using biotin-NAD+, NAD+ and sIDNA as substrate at 5 uM incubated for 1 hr by ELISA relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4618663 | B | Inhibition of N-terminal His-tagged thioredoxin-fused human ARTD12 (469 to 701 residues) expressed in Escherichia coli Rosetta2 (DE3) after 20 hrs in presence of NAD+ | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 15. | ALA4678523 | B | Inhibition of PARP-12 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4701312 | B | Inhibition of N-terminal His-GST tagged human PARP12 (500 to 701 residues) expressed in baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ribosylation using histone as substrate at 10 uM incubated for 1 hr in presence of biotinylated NAD+ and activated DNA by chemiluminescence based microplate reader assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA5030396 | B | Inhibition of PARP12 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 18. | ALA5108313 | B | Inhibition of N-terminal His-tagged human PARP12 catalytic domain expressed in Escherichia coli BL21 (DE3) at 10 uM preincubated with 6-a-NAD+ for 5 to 10 mins followed by enzyme addition and measured after 60 mins using NAD+ as substrate byHRP based chemiluminescence assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 19. | ALA5123569 | B | Inhibition of human PARP12 | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 20. | ALA5123675 | B | Inhibition of PARP-12 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature |
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