# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2432859 | B | Inhibition of STEP in Sprague-Dawley rat embryo primary cortical neurons assessed as phosphorylation of GluN2B at 0.1 to 10 uM after 1 hr by Western blot analysis | Rattus norvegicus | 2 | ALA2429849 | single protein format | Scientific Literature | |
2. | ALA2432860 | B | Inhibition of STEP in Sprague-Dawley rat embryo primary cortical neurons assessed as phosphorylation of Pyk2 at 0.1 to 10 uM after 1 hr by Western blot analysis | Rattus norvegicus | 2 | ALA2429849 | single protein format | Scientific Literature | |
3. | ALA2432861 | B | Inhibition of STEP in Sprague-Dawley rat embryo primary cortical neurons assessed as phosphorylation of ERK1/2 at 0.1 to 10 uM after 1 hr by Western blot analysis | Rattus norvegicus | 2 | ALA2429849 | single protein format | Scientific Literature | |
4. | ALA4768208 | B | Inhibition of STEP in serum deprived rat PC-12 cells assessed as increase in NGF-induced ERK1/2 phosphorylation at T202/Y204 pretreated at 20 uM for 2 hrs followed by stimulated with NGF for 5 mins by Western blotting analysis | Rattus norvegicus | 4 | ALA4765268 | tissue-based format | Scientific Literature | |
5. | ALA4768209 | B | Inhibition of STEP in serum deprived rat PC-12 cells assessed as increase in NGF-induced Pyk2 phosphorylation at Y412 pretreated at 20 uM for 2 hrs followed by stimulated with NGF for 5 mins by Western blotting analysis | Rattus norvegicus | 4 | ALA4765268 | tissue-based format | Scientific Literature |