| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA819810 | F | Effective dose against LPS-stimulated Tumor necrosis factor, alpha release in mice dosed orally, 30 min prior to LPS challenge (0.1 mg/kg, ip) | Mus musculus | 9 | organism-based format | Scientific Literature | ||
| 2. | ALA819811 | F | Effective dose against LPS-stimulated Tumor necrosis factor, alpha release in mice dosed orally, 30 min prior to LPS challenge (0.1 mg/kg, ip); ND is No Data | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA819812 | F | Effective dose against LPS-stimulated Tumor necrosis factor, alpha release in mice dosed orally, 30 min prior to LPS challenge (0.1 mg/kg, ip); ND is No Data. | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA819935 | F | Effective dose against LPS-stimulated Tumor necrosis factor, alpha release in mice dosed orally, 30 min prior to LPS challenge (0.1 mg/kg, ip); value ranges from 3-10 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA826224 | F | In vitro percent inhibition of tumor necrosis factor, alpha secreted by macrophage at the dose 1 ug/mL | 16 | assay format | Scientific Literature | |||
| 6. | ALA826239 | F | In vitro percent inhibition of tumor necrosis factor, alpha secreted by macrophage at the dose 10 ug/mL | 16 | assay format | Scientific Literature | |||
| 7. | ALA826248 | F | In vitro percent inhibition of tumor necrosis factor, alpha secreted by macrophage at the dose 100 ug/mL | 16 | assay format | Scientific Literature | |||
| 8. | ALA1274303 | B | Inhibition of TNFalpha in LPS-stimulated mouse RAW264.7 cells at 10 uM after 2 hrs treated after 14 hrs of LPS challenge by FACS analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 9. | ALA4186499 | B | Inhibition of mouse recombinant TNF-alpha binding to antibody preincubated for 30 mins followed by antibody addition measured after 2 hrs by ELISA | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4630416 | B | Inhibition of TNF-alpha in mouse RAW264.7 cells assessed as inhibition of LPS-induced IKBalpha phosphorylation at 5 to 20 uM pre-incubated for 12 hrs before LPS stimulation for 2 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4630417 | B | Inhibition of TNF-alpha in mouse RAW264.7 cells assessed as inhibition of LPS-induced IKBalpha phosphorylation at 5 to 20 uM pre-incubated for 12 hrs before LPS stimulation for 2 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4630418 | B | Inhibition of TNF-alpha in mouse RAW264.7 cells assessed as inhibition of NFkappB/p65 nuclear translocation at 5 to 20 uM by DAPI staining based microscopy | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4775698 | B | Inhibition of TNFalpha in mouse L929 cells exposed to compound incubated for 1 hr with mouse TNFalpha by luminescence based assay | Mus musculus | 11 | cell-based format | Scientific Literature | ||
| 14. | ALA5228022 | B | Inhibition of mouse TNF-alpha in mouse L929 cells incubated for 18 hrs by CellTitreGlo assay | Mus musculus | 1 | cell-based format | Scientific Literature |
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