# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA650670 | B | Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assay | Homo sapiens | 13 | ALA1133826 | single protein format | Scientific Literature | |
2. | ALA876407 | B | Concentration required to inhibit complement component 3a (C3a) binding to C3a receptor in human neutrophil based assay; Not active at 25 uM | 1 | ALA1133826 | single protein format | Scientific Literature | ||
3. | ALA650671 | B | Concentration required to inhibit complement component 3a (C3a) binding to C3a receptor in human neutrophil based assay; Not active at 25 uM | 4 | ALA1133826 | single protein format | Scientific Literature | ||
4. | ALA795442 | F | Percent inhibition against C3a receptor induced wheal formation in rat at the dose of 15 mg/Kg administered orally | Rattus norvegicus | 3 | ALA1133826 | assay format | Scientific Literature | |
5. | ALA795443 | F | Percent inhibition against C3a receptor induced wheal formation in rat at the dose of 30 mg/Kg administered intraperitoneally | Rattus norvegicus | 5 | ALA1133826 | assay format | Scientific Literature | |
6. | ALA795444 | F | Percent inhibition against C3a receptor induced wheal formation in rat at the dose of 30 mg/Kg administered orally | Rattus norvegicus | 5 | ALA1133826 | assay format | Scientific Literature | |
7. | ALA889062 | B | Inhibition of human C3a receptor expressed on HMC1 cells by SPA assay | Homo sapiens | 22 | ALA1145356 | cell-based format | Scientific Literature | |
8. | ALA889063 | F | Antagonist activity at C3aR | Homo sapiens | 4 | ALA1145356 | assay format | Scientific Literature | |
9. | ALA889064 | F | Agonist activity at C3a receptor expressed on HMC1 cells | Homo sapiens | 3 | ALA1145356 | cell-based format | Scientific Literature | |
10. | ALA894522 | B | Displacement of [125I]C3a from human C3a receptor expressed in HMC1 cells co-expressing aequorin | Homo sapiens | 38 | ALA1148022 | cell-based format | Scientific Literature | |
11. | ALA894528 | F | Antagonist activity at human C3a receptor expressed in HMC1 cells co-expressing aequorin | Homo sapiens | 2 | ALA1148022 | cell-based format | Scientific Literature | |
12. | ALA894529 | F | Agonist activity at human C3a receptor expressed in HMC1 cells co-expressing aequorin | Homo sapiens | 5 | ALA1148022 | cell-based format | Scientific Literature | |
13. | ALA1176063 | F | Agonist activity at human C3a receptor in human U937 cells assessed as induction of intracellular calcium release at 1 mM | Homo sapiens | 24 | ALA1177720 | cell-based format | Scientific Literature | |
14. | ALA1176064 | B | Displacement of [125I-C3a] from C3a receptor in human PBMC at 1 mM by scintillation counting | Homo sapiens | 3 | ALA1177720 | single protein format | Scientific Literature | |
15. | ALA1176066 | F | Agonist activity at human C3a receptor in human U937 cells assessed as induction of intracellular calcium release | Homo sapiens | 41 | ALA1177720 | cell-based format | Scientific Literature | |
16. | ALA1176068 | B | Displacement of [125I-C3a] from C3a receptor in human PBMC by scintillation counting | Homo sapiens | 19 | ALA1177720 | single protein format | Scientific Literature | |
17. | ALA1176069 | F | Antagonist activity at human C3a receptor in human U937 cells assessed as inhibition of intracellular calcium mobilization | Homo sapiens | 2 | ALA1177720 | cell-based format | Scientific Literature | |
18. | ALA1176070 | F | Agonist activity at human C3a receptor in human U937 cells assessed as induction of intracellular calcium release at 10 uM | Homo sapiens | 4 | ALA1177720 | cell-based format | Scientific Literature | |
19. | ALA1176071 | F | Agonist activity at human C3a receptor in human U937 cells assessed as induction of intracellular calcium release at 100 uM | Homo sapiens | 1 | ALA1177720 | cell-based format | Scientific Literature | |
20. | ALA2066635 | F | Agonist activity at human C3a receptor expressed in RBL-2H3 cells assessed as beta-hexosaminidase activity in cell supernatant by degranulation assay relative to recombinant human C3a | Homo sapiens | 12 | ALA2062398 | cell-based format | Scientific Literature |