# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2343139 | B | Inhibition of rat alpha9/alpha10 nAChR expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced currents after 300 secs by two-electrode voltage clamp assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
2. | ALA2400257 | B | Activity at rat recombinant alpha9alpha10 nAChR expressed in Xenopus oocytes assessed as effect on acetylcholine-induced response at 3 uM by two-electrode voltage clamp technique relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
3. | ALA3106795 | B | Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current at 10 uM after 2 to 4 days by voltage clamp electrophysiology method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
4. | ALA3107561 | B | Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current after 2 to 4 days by voltage clamp electrophysiology method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
5. | ALA3107576 | B | Antagonist activity at Sprague-Dawley rat alpha9alpha10 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiology method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
6. | ALA3107582 | B | Inhibition of recombinant rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiology method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
7. | ALA3375969 | B | Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus oocytes assessed as inhibition of Ach-evoked current after 5 mins by voltage-clamp technique | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
8. | ALA3375971 | B | Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus oocytes assessed as inhibition of Ach-evoked current at 3 uM after 5 mins by voltage-clamp technique | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
9. | ALA3375973 | B | Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus oocytes assessed as inhibition of Ach-evoked current at 30 uM after 5 mins by voltage-clamp technique | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
10. | ALA4013134 | B | Antagonist activity at rat alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
11. | ALA4202187 | B | Antagonist activity at rat alpha9alpha10 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents pre-incubated for 5 mins prior to acetyl choline pulse at -70 mV potential by two-electrode voltage clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
12. | ALA4202195 | B | Antagonist activity at rat alpha9alpha10 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents at 10 uM pre-incubated for 5 mins prior to acetyl choline pulse at -70 mV potential by two-electrode voltage clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
13. | ALA4358816 | B | Inhibition of rat alpha9alpha10 nAChR | Rattus norvegicus | 3 | protein complex format | Scientific Literature | ||
14. | ALA4365269 | B | Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
15. | ALA4381855 | B | Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 15 | cell-based format | Scientific Literature | ||
16. | ALA4381862 | B | Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at 10 nM at -70 mV holding potential preincubated for 5 mins followed by compound washout by two electrode voltage-clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
17. | ALA4682094 | B | Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -80 mV holding potential preincubated for 5 mins followed by Ach stimulation by two electrode voltage-clamp assay | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
18. | ALA4811732 | B | Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
19. | ALA4811765 | B | Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response at 10 uM by two-electrode voltage-clamp method relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
20. | ALA5055998 | B | Antagonist activity at rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential preincubated for 5 mins followed by Ach stimulation by voltage-clamp based electrophysiological method | Rattus norvegicus | 5 | cell-based format | Scientific Literature |