| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1011060 | B | Inhibition of Cdk2/cyclin A at 100 nM relative to control | 1 | ALA1139385 | protein complex format | Scientific Literature | ||
| 2. | ALA2380114 | B | Inhibition of human CDK2/Cyclin A1 at 0.1 uM incubated for 15 mins prior to substrate addition measured after 90 mins by P33-radiolabeled assay relative to control | Homo sapiens | 1 | ALA2375244 | protein complex format | Scientific Literature | |
| 3. | ALA2380182 | B | Inhibition of CDK2/Cyclin A1 (unknown origin)-mediated phosphorylation of peptide substrate incubated for 15 mins prior to substrate addition measured after 90 mins by P33-radiolabeled assay | Homo sapiens | 2 | ALA2375244 | protein complex format | Scientific Literature | |
| 4. | ALA3632298 | B | Inhibition of CDK2/Cyclin A1 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | ALA3627608 | protein complex format | Scientific Literature | |
| 5. | ALA3750383 | B | Inhibition of CDK2/Cyclin A (unknown origin) | Homo sapiens | 1 | ALA3745712 | protein complex format | Scientific Literature | |
| 6. | ALA3748658 | B | Inhibition of human CDK2/Cyclin A1 using histone H1 as substrate | Homo sapiens | 1 | ALA3745707 | protein complex format | Scientific Literature | |
| 7. | ALA3856477 | B | Inhibition of recombinant human His/GST-tagged CDK2/Cyclin A expressed in baculovirus infected Sf9 cells using Histone H1 as substrate after 80 mins in presence of [33P]ATP by microbeta scintillation counting analysis | Homo sapiens | 2 | ALA3856187 | cell-based format | Scientific Literature | |
| 8. | ALA4059185 | B | Inhibition of human CDK2/Cyclin A1 using histone H1 as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition measure after 120 mins by filter binding method | Homo sapiens | 39 | ALA4052828 | protein complex format | Scientific Literature | |
| 9. | ALA4059186 | B | Inhibition of human CDK2/Cyclin A1 assessed as residual activity at 0.123 uM using histone H1 as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition measure after 120 mins by filter binding method relative to control | Homo sapiens | 6 | ALA4052828 | protein complex format | Scientific Literature | |
| 10. | ALA4059191 | B | Potency index, ratio of AT7519 IC50 to test compound IC50 for human CDK2/Cyclin A1 | Homo sapiens | 2 | ALA4052828 | protein complex format | Scientific Literature | |
| 11. | ALA4315508 | B | Inhibition of recombinant human N-terminal GST-tagged full length CDK2/CyclinA1 expressed in baculovirus infected Sf9 insect cells assessed as enzyme activity incubated for 15 mins by [gamma-33]ATP based scintillation counting method relative to control | Homo sapiens | 4 | ALA4312005 | cell-based format | Scientific Literature | |
| 12. | ALA4324324 | B | Binding affinity to recombinant human full length N-terminal GST-tagged CDK2/Cyclin A1 expressed in baculovirus infected Sf9 cells at 1 uM relative to control | Homo sapiens | 1 | ALA4321846 | cell-based format | Scientific Literature | |
| 13. | ALA4324326 | B | Inhibition of recombinant human full length His-tagged CDK2/Cyclin A expressed in baculovirus expression system at 1 uM relative to control | Homo sapiens | 1 | ALA4321846 | assay format | Scientific Literature | |
| 14. | ALA4327510 | B | Inhibition of human CDK2/cyclin-A1 assessed as residual activity at 1 uM using histone H1 as substrate by [gamma-33P]-ATP assay relative to control | Homo sapiens | 2 | ALA4325871 | protein complex format | Scientific Literature | |
| 15. | ALA4328661 | B | Inhibition of human CDK2/cyclin-A1 assessed as residual activity at 100 uM using histone H1 as substrate by [gamma-33P]-ATP assay relative to control | Homo sapiens | 1 | ALA4325871 | protein complex format | Scientific Literature | |
| 16. | ALA4328662 | B | Inhibition of human CDK2/cyclin-A1 using histone H1 as substrate by [gamma-33P]-ATP assay | Homo sapiens | 1 | ALA4325871 | protein complex format | Scientific Literature | |
| 17. | ALA4334999 | B | Inhibition of recombinant full length human CDK2/CyclinA assessed as residual activity at 1 uM using Histone H1 as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | protein complex format | Scientific Literature | |
| 18. | ALA4336827 | B | Inhibition of recombinant full length human CDK2/CyclinA assessed as residual activity at 10 uM using Histone H1 as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | protein complex format | Scientific Literature | |
| 19. | ALA4366328 | B | Inhibition of human CDK2/cyclin-A1 at 100 nM using histone H1 as substrate by [gamma-33P]-ATP assay | Homo sapiens | 1 | ALA4364276 | protein complex format | Scientific Literature | |
| 20. | ALA4379169 | B | Inhibition of recombinant full length human CDK2/CyclinA using Histone H1 as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiometric scintillation counting analysis | Homo sapiens | 1 | ALA4376834 | protein complex format | Scientific Literature |
The page will load shortly, Thanks for your patience!