# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3578486 | Binding | Inhibition of human full length N-terminal GST-fusion protein CDK4/GST-tagged Cyclin D3 expressed in baculovirus using DYRKtide-F as substrate at 0.1 uM after 1 hr by off-chip Mobility Shift Assay | Homo sapiens | 1 | ALA3576861 | assay format | Scientific Literature | |
2. | ALA3632302 | Binding | Inhibition of CDK4/cyclin D3 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | ALA3627608 | protein complex format | Scientific Literature | |
3. | ALA3748662 | Binding | Inhibition of human CDK4/cyclin D3 using RB-CTF as substrate | Homo sapiens | 1 | ALA3745707 | protein complex format | Scientific Literature | |
4. | ALA3802148 | Binding | Inhibition of human recombinant CDK4/Cyclin D3 expressed in sf21 cells using Rb (773 to 928 residues) as substrate by radiometric assay in presence of gamma[32P]ATP | Homo sapiens | 1 | ALA3797159 | cell-based format | Scientific Literature | |
5. | ALA3817236 | Binding | Inhibition of human CDK4/cyclin D3 at 1 uM using RB-CTF as substrate | Homo sapiens | 1 | ALA3813650 | protein complex format | Scientific Literature | |
6. | ALA1174107 | Binding | Inhibition of CDK4/cyclin D3 at 10 uM | 2 | ALA1177794 | protein complex format | Scientific Literature | ||
7. | ALA4351782 | Binding | Inhibition of recombinant full-length human CDK4/cyclinD3 at 10 uM using Rb fragment as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting method | Homo sapiens | 1 | ALA4350961 | protein complex format | Scientific Literature | |
8. | ALA4352311 | Binding | Inhibition of human CDK4/cyclin-D3 at 10 uM using RB-CTF as substrate in presence of [gamma-33P]-ATP | Homo sapiens | 1 | ALA4350963 | protein complex format | Scientific Literature | |
9. | ALA4357802 | Binding | Binding affinity to wild-type human full length CDK4/cyclinD3 (M1 to E303 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4354843 | assay format | Scientific Literature | |
10. | ALA1066634 | Binding | Residual activity of CDK4/Cyclin D3 at 0.1 uM by microplate scintillation counting | 3 | ALA1152560 | protein complex format | Scientific Literature | ||
11. | ALA1050420 | Binding | Residual activity of CDK4/Cyclin D3 at 1 uM by microplate scintillation counting | 3 | ALA1152560 | protein complex format | Scientific Literature | ||
12. | ALA1047833 | Binding | Residual activity of CDK4/Cyclin D3 at 10 uM by microplate scintillation counting | 3 | ALA1152560 | protein complex format | Scientific Literature | ||
13. | ALA2209334 | Binding | Inhibition of CDK4-cyclinD3 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | protein complex format | Scientific Literature | ||
14. | ALA2380161 | Binding | Inhibition of human CDK4/Cyclin D3 at 0.1 uM incubated for 15 mins prior to substrate addition measured after 90 mins by P33-radiolabeled assay relative to control | Homo sapiens | 1 | ALA2375244 | protein complex format | Scientific Literature | |
15. | ALA3225103 | Binding | Inhibition of CDK4/cyclin-D3 (unknown origin) | Homo sapiens | 1 | ALA3217424 | protein complex format | Scientific Literature | |
16. | ALA3881036 | Binding | Inhibition of human CDK4/cyclin D3 expressed in Escherichia coli using retinoblastoma (386 to 928 residues) as substrate after 20 mins by gamma32P-ATP based scintillation counting analysis | Homo sapiens | 45 | ALA3880421 | assay format | Patent Bioactivity Data | |
17. | ALA3881037 | Binding | Inhibition of human CDK4/cyclin D3 expressed in Escherichia coli at 1 uM using retinoblastoma (386 to 928 residues) as substrate after 20 mins by gamma32P-ATP based scintillation counting analysis | Homo sapiens | 20 | ALA3880421 | assay format | Patent Bioactivity Data | |
18. | ALA3881058 | Binding | Inhibition of human CDK4/cyclin D3 expressed in Escherichia coli at 5 uM using retinoblastoma (386 to 928 residues) as substrate after 20 mins by gamma32P-ATP based scintillation counting analysis | Homo sapiens | 2 | ALA3880421 | assay format | Patent Bioactivity Data | |
19. | ALA4003773 | Binding | Inhibition of human CDK4/cyclinD3 using Histone H1 as substrate in presence of [gamma-33P]ATP after 40 mins by scintillation counter method | Homo sapiens | 17 | ALA4002601 | protein complex format | Scientific Literature | |
20. | ALA4024282 | Binding | Inhibition of recombinant human full length N-terminal GST-tagged CDK4/Cyclin-D3 co-expressed in baculovirus infected sf21 cells at 1 uM using Rb substrate in presence of [gamma33P]ATP after 10 mins by scintillation counting method relative to control | Homo sapiens | 1 | ALA4020842 | cell-based format | Scientific Literature |