# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1066639 | Binding | Residual activity of CDK8/Cyclin C at 0.1 uM by microplate scintillation counting | 3 | ALA1152560 | protein complex format | Scientific Literature | ||
2. | ALA1037101 | Binding | Residual activity of CDK8/Cyclin C at 1 uM by microplate scintillation counting | 3 | ALA1152560 | protein complex format | Scientific Literature | ||
3. | ALA1044269 | Binding | Residual activity of CDK8/Cyclin C at 10 uM by microplate scintillation counting | 3 | ALA1152560 | protein complex format | Scientific Literature | ||
4. | ALA4387199 | Binding | Inhibition of tracer 236 binding to recombinant full length human His-tagged CDK8/cyclin C expressed in baculovirus expression system at 0.1 uM measured after 60 mins by Lanthascreen assay | Homo sapiens | 2 | ALA4385643 | assay format | Scientific Literature | |
5. | ALA3854801 | Binding | Inhibition of Alexa647 tracer binding to full length recombinant human His-tagged CDK8/cyclin C expressed in Baculovirus expression system preincubated for 20 mins followed by tracer addition and incubated in dark for 60 mins by FRET-based Lanthascreen assay | Homo sapiens | 24 | ALA3853318 | assay format | Scientific Literature | |
6. | ALA3854816 | Binding | Inhibition of Alexa647 tracer binding to full length recombinant human His-tagged CDK8/cyclin C expressed in Baculovirus expression system at 1 uM preincubated for 20 mins followed by tracer addition and incubated in dark for 60 mins by FRET-based Lanthascreen assay relative to control | Homo sapiens | 7 | ALA3853318 | assay format | Scientific Literature | |
7. | ALA3854826 | Binding | Binding affinity to human CDK8 (1 to 464 residues)/cyclin C (1 to 283 residues) by reporter displacement assay | Homo sapiens | 1 | ALA3853318 | protein complex format | Scientific Literature | |
8. | ALA3854828 | Binding | Binding affinity to human CDK8 (1 to 464 residues)/cyclin C (1 to 283 residues) assessed as residence time by reporter displacement assay | Homo sapiens | 1 | ALA3853318 | protein complex format | Scientific Literature | |
9. | ALA3856520 | Binding | Inhibition of CDK8/cyclin C (unknown origin) using RBER-CHKStide as substrate after 60 mins in presence of 33P-ATP by microbeta scintillation counting analysis | Homo sapiens | 1 | ALA3856187 | protein complex format | Scientific Literature | |
10. | ALA4366341 | Binding | Inhibition of human CDK8/cyclin-C at 100 nM using KKKVSRSGLYRSPSMPENLNRPR as substrate by [gamma-33P]-ATP assay | Homo sapiens | 1 | ALA4364276 | protein complex format | Scientific Literature | |
11. | ALA2405929 | Binding | Inhibition of CDK8/cyclin C (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA2401733 | protein complex format | Scientific Literature | |
12. | ALA3404923 | Binding | Binding affinity to CDK8/CycC (unknown origin) assessed as residence time | Homo sapiens | 2 | ALA3400049 | protein complex format | Scientific Literature | |
13. | ALA3631706 | Binding | Inhibition of CDKB/cyclinC (unknown origin) at 1 uM by FRET method | Homo sapiens | 1 | ALA3627690 | protein complex format | Scientific Literature | |
14. | ALA3751087 | Binding | Inhibition of CDK8/cyclinC (unknown origin) at 1 uM | Homo sapiens | 1 | ALA3745631 | protein complex format | Scientific Literature | |
15. | ALA3762300 | Binding | Inhibition of CDK8/cyclinC (unknown origin) at 100 nM | Homo sapiens | 2 | ALA3758169 | protein complex format | Scientific Literature | |
16. | ALA3779191 | Binding | Displacement of dye-labeled ATP competitive probe from recombinant human CDK8/Cyclin C incubated for 20 mins by Alexa647 probe-based FRET assay | Homo sapiens | 32 | ALA3774357 | protein complex format | Scientific Literature | |
17. | ALA3779194 | Binding | Binding affinity to CDK8/Cyclin C (unknown origin) assessed as residence time by reporter displacement assay | Homo sapiens | 2 | ALA3774357 | protein complex format | Scientific Literature | |
18. | ALA3779200 | Binding | Binding affinity to CDK8/Cyclin C (unknown origin) by reporter displacement assay | Homo sapiens | 2 | ALA3774357 | protein complex format | Scientific Literature | |
19. | ALA3803458 | Binding | Binding affinity to human CDK8 (1 to 464 amino acid residues)/Cyclin C (1 to 283 amino acid residues) assessed as residence time by reporter displacement assay | Homo sapiens | 1 | ALA3797072 | protein complex format | Scientific Literature | |
20. | ALA3803459 | Binding | Binding affinity to human CDK8 (1 to 464 amino acid residues)/Cyclin C (1 to 283 amino acid residues) by reporter displacement assay | Homo sapiens | 1 | ALA3797072 | protein complex format | Scientific Literature |