# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA662350 | B | Maximal noneffective concentration for inhibition of DNA gyrase using supercoiling assay. | Staphylococcus aureus | 19 | ALA1133769 | protein complex format | Scientific Literature | |
2. | ALA813922 | F | In vivo efficacy against Staphylococcus aureus NCTC-10649M after oral administration | Staphylococcus aureus | 27 | ALA1129258 | organism-based format | Scientific Literature | |
3. | ALA813923 | F | In vivo efficacy against Staphylococcus aureus NCTC-10649M after subcutaneous administration | Staphylococcus aureus | 28 | ALA1129258 | organism-based format | Scientific Literature | |
4. | ALA810326 | F | In vitro antibacterial activity against gram-positive organism Staphylococcus aureus 1775 | Staphylococcus aureus | 59 | ALA1129258 | assay format | Scientific Literature | |
5. | ALA810327 | F | In vitro antibacterial activity against gram-positive organism Staphylococcus aureus ATCC 6538p | Staphylococcus aureus | 60 | ALA1129258 | assay format | Scientific Literature | |
6. | ALA810328 | F | In vitro antibacterial activity against gram-positive organism Staphylococcus aureus NCTC-10649M | Staphylococcus aureus | 60 | ALA1129258 | assay format | Scientific Literature | |
7. | ALA840006 | B | Stimulation of DNA cleavage complex formation in DNA gyrase from Staphylococcus aureus ISP 794 | Staphylococcus aureus | 1 | ALA1141145 | protein complex format | Scientific Literature | |
8. | ALA840008 | B | Stimulation of DNA cleavage complex formation in DNA gyrase from Staphylococcus aureus ISP 794; Range = 30-50 ug/ml | Staphylococcus aureus | 1 | ALA1141145 | protein complex format | Scientific Literature | |
9. | ALA840009 | B | Stimulation of DNA cleavage complex formation in DNA gyrase from Staphylococcus aureus ISP 794; Range = 12.5-25 ug/ml | Staphylococcus aureus | 1 | ALA1141145 | protein complex format | Scientific Literature | |
10. | ALA826975 | F | Inhibition of supercoiling activity of DNA gyrase from Staphylococcus aureus ISP 794 | Staphylococcus aureus | 2 | ALA1141145 | assay format | Scientific Literature | |
11. | ALA832740 | B | Inhibitory concentration against DNA gyrase of Staphylococcus aureus | Staphylococcus aureus | 4 | ALA1143629 | protein complex format | Scientific Literature | |
12. | ALA828150 | F | Inhibition of supercoiling activity of DNA gyrase from Staphylococcus aureus ISP 794; Range = 2.5-5 ug/mL | Staphylococcus aureus | 1 | ALA1141145 | assay format | Scientific Literature | |
13. | ALA854375 | B | Inhibition of DNA gyrase supercoiling in Staphylococcus aureus ATCC 29213 | Staphylococcus aureus | 4 | ALA1148591 | protein complex format | Scientific Literature | |
14. | ALA910511 | B | Inhibition of Staphylococcus aureus DNA gyrase by supercoiling assay | Staphylococcus aureus | 7 | ALA1139232 | protein complex format | Scientific Literature | |
15. | ALA1004727 | B | Inhibition of Staphylococcus aureus DNA gyrase | Staphylococcus aureus | 22 | ALA1139395 | protein complex format | Scientific Literature | |
16. | ALA989568 | B | Inhibition of Staphylococcus aureus DNA gyrase | Staphylococcus aureus | 9 | ALA1143389 | protein complex format | Scientific Literature | |
17. | ALA983305 | B | Induction of Staphylococcus aureus DNA gyrase-mediated negatively supercoiled Escherichia coli pBR322 DNA cleavage at 50 uM after 10 mins by gel electrophoresis | Staphylococcus aureus | 1 | ALA1154411 | protein complex format | Scientific Literature | |
18. | ALA983312 | B | Induction of Staphylococcus aureus DNA gyrase-mediated Escherichia coli pBR322 DNA cleavage assessed as ratio of drug-induced DNA cleavage to spontaneous DNA cleavage at 50 uM after 10 mins by gel electrophoresis | Staphylococcus aureus | 1 | ALA1154411 | protein complex format | Scientific Literature | |
19. | ALA968425 | B | Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity | Staphylococcus aureus | 9 | ALA1157150 | protein complex format | Scientific Literature | |
20. | ALA1005220 | B | Inhibition of Staphylococcus aureus MS5935 wild type DNA gyrase-mediated supercoiling activity | Staphylococcus aureus | 3 | ALA1150336 | protein complex format | Scientific Literature |