| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2410092 | B | Competitive inhibition of recombinant HDAC3-NCoR1 (unknown origin) assessed as fast tight binding at 0.016 to 1 uM | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 2. | ALA2410093 | B | Inhibition of recombinant HDAC3-NCoR1 (unknown origin) assessed as slow tight binding at 0.02 to 20 uM | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 3. | ALA2410097 | B | Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins by fluorescence plate reader analysis | Homo sapiens | 29 | protein complex format | Scientific Literature | ||
| 4. | ALA2423465 | B | Inhibition of GST-tagged recombinant human HDAC3/NcoR1 enzyme using flurogenic Ac-LeuGlyLys (Ac)-AMC as substrate at 50 uM after 15 to 30 mins | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
| 5. | ALA2423476 | B | Inhibition of GST-tagged recombinant human HDAC3/NcoR1 enzyme using flurogenic Ac-LeuGlyLys (Ac)-AMC as substrate after 15 to 30 mins | Homo sapiens | 7 | protein complex format | Scientific Literature | ||
| 6. | ALA3801291 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as residual enzyme activity using fluorogenic Ac-LGK-ac-AMC as substrate for 30 mins by fluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3801292 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as residual enzyme activity preincubated for 15 mins followed by addition of fluorogenic Ac-LGK-ac-AMC as substrate for 30 mins by fluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3801293 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as residual enzyme activity preincubated for 30 mins followed by addition of fluorogenic Ac-LGK-ac-AMC as substrate for 30 mins by fluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3801294 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as residual enzyme activity preincubated for 1 hr followed by addition of fluorogenic Ac-LGK-ac-AMC as substrate for 30 mins by fluorescence analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA3802963 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as residual enzyme activity preincubated for 2 hrs followed by addition of fluorogenic Ac-LGK-ac-AMC as substrate for 30 mins by fluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3802974 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as inhibition constant ki,1 using fluorogenic Ac-LGK-ac-AMC as substrate by fluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3802975 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as inhibition constant k2 using fluorogenic Ac-LGK-ac-AMC as substrate by fluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3802976 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as inhibition constant k'-2 using fluorogenic Ac-LGK-ac-AMC as substrate by fluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4019753 | B | Inhibition of human recombinant HDAC3/GST tagged NCOR1 (397 to 503 residues) expressed in insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4037055 | B | Inhibition of human recombinant HDAC3/NCOR1 co-expressed in insect cells by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4144349 | B | Inhibition of human recombinant HDAC3/GST-tagged NCOR1 DAD (397 to 503 residues) expressed in baculovirus expression system after 30 mins by fluorescence assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 17. | ALA4150581 | B | Inhibition of human recombinant HDAC3/GST-tagged NCOR1 (397 to 503 residues) co-expressed in insect cells using (Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA4258316 | B | Inhibition of recombinant human HDAC3/NCOR1 using FLUOR DE LYS SIRT1 deacetylase substrate after 1 hr by fluorescence assay | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 19. | ALA4322087 | B | Inhibition of recombinant human HDAC3/GST-tagged NCOR1 DAD (397 to 503 residues) expressed in baculovirus expression system using Fluor de Lys as substrate by fluorescence assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 20. | ALA4397963 | B | Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed by substrate addition and and measured after 30 mins by fluorescence based assay | Homo sapiens | 6 | protein complex format | Scientific Literature |
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