# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3579952 | Binding | Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometry | Homo sapiens | 2 | ALA3576868 | assay format | Scientific Literature | |
2. | ALA3579953 | Binding | Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometry | Homo sapiens | 2 | ALA3576868 | assay format | Scientific Literature | |
3. | ALA3579955 | Binding | Inhibition of beta-N-acetylhexosaminidase (unknown origin) | Homo sapiens | 1 | ALA3576868 | protein format | Scientific Literature | |
4. | ALA3579956 | Binding | Inhibition of human placental HexA using pNPGlcNAc substrate | Homo sapiens | 17 | ALA3576868 | assay format | Scientific Literature | |
5. | ALA3579966 | Binding | Inhibition of HexA in normal human fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometry | Homo sapiens | 2 | ALA3576868 | single protein format | Scientific Literature | |
6. | ALA3580142 | Binding | Induction of wild type HexA activity in non-GM2 gangliosidosis patient fibroblasts at 33 ug/ml incubated for 5 days | Homo sapiens | 2 | ALA3576868 | single protein format | Scientific Literature | |
7. | ALA3853691 | Binding | Inhibition of beta-hexosaminidase alpha/beta in human skin fibroblast lysate using 4-MU-(2-acetamido-2-deoxy)-beta-D-glucopyranoside as substrate assessed as 4-MU liberation by fluorescence assay | Homo sapiens | 2 | ALA3853269 | assay format | Scientific Literature | |
8. | ALA2388712 | Binding | Competitive inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate at 0.1 mM incubated for 10 mins prior to substrate addition by Dixon plot analysis | Homo sapiens | 1 | ALA2384927 | protein format | Scientific Literature | |
9. | ALA2388713 | Binding | Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate at 50 uM incubated for 10 mins prior to substrate addition by spectrofluorometric analysis relative to control | Homo sapiens | 11 | ALA2384927 | protein format | Scientific Literature | |
10. | ALA2388714 | Binding | Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins prior to substrate addition by spectrofluorometric analysis | Homo sapiens | 31 | ALA2384927 | protein format | Scientific Literature |