| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2427285 | B | Voltage dependent inhibition of GluN1/GluN2D receptor (unknown origin) expressed in Xenopus laevis oocytes at 30 mV at 1 uM by two-electrode voltage-clamp electrophysiology assay | Homo sapiens | 1 | ALA2424574 | cell-based format | Scientific Literature | |
| 2. | ALA2427286 | B | Voltage dependent inhibition of GluN1/GluN2D receptor (unknown origin) expressed in Xenopus laevis oocytes at -40 mV at 1 uM by two-electrode voltage-clamp electrophysiology assay | Homo sapiens | 1 | ALA2424574 | cell-based format | Scientific Literature | |
| 3. | ALA2427686 | B | Inhibition of GluN1/GluN2D receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at 3 uM by two-electrode voltage clamp method | Homo sapiens | 2 | ALA2424574 | cell-based format | Scientific Literature | |
| 4. | ALA2427892 | B | Noncompetitive inhibition of GluN1/GluN2D receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of 3 mM of glutamate/glycine-induced current at 1 uM by two-electrode voltage-clamp electrophysiology assay | Homo sapiens | 1 | ALA2424574 | cell-based format | Scientific Literature | |
| 5. | ALA2427893 | B | Noncompetitive inhibition of GluN1/GluN2D receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of 30 uM of glutamate/glycine-induced current at 1 uM by two-electrode voltage-clamp electrophysiology assay | Homo sapiens | 1 | ALA2424574 | cell-based format | Scientific Literature | |
| 6. | ALA3594877 | B | Inhibition of recombinant GluN1/GluN2D receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whole-cell voltage-clamp method | Homo sapiens | 1 | ALA3593227 | cell-based format | Scientific Literature | |
| 7. | ALA3801524 | B | Positive allosteric modulation of GluN1/GluN2D NMDAR (unknown origin) expressed in Dox-inducible cells by BD calcium indicator dye based-fluorescence analysis in presence of glutamate/glycine | Homo sapiens | 1 | ALA3797125 | cell-based format | Scientific Literature | |
| 8. | ALA3801525 | B | Positive allosteric modulation of GluN1/GluN2D NMDAR (unknown origin) expressed in Dox-inducible cells at 125 uM by BD calcium indicator dye based-fluorescence analysis in presence of glutamate/glycine | Homo sapiens | 1 | ALA3797125 | cell-based format | Scientific Literature | |
| 9. | ALA3871172 | B | Positive allosteric modulation of GluN1/GluN2D receptor (unknown origin) assessed as increase in glutamate-induced calcium flux measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay | Homo sapiens | 1 | ALA3870360 | protein complex format | Scientific Literature | |
| 10. | ALA3871173 | B | Positive allosteric modulation of GluN1/GluN2D receptor (unknown origin) assessed as increase in glutamate-induced calcium flux at 125 uM measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay | Homo sapiens | 1 | ALA3870360 | protein complex format | Scientific Literature | |
| 11. | ALA4309028 | B | Negative allosteric modulation of GluN1a/GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glutamate/glycine-induced channel current at -60 mV holding potential by two electrode voltage clamp method | Homo sapiens | 1 | ALA4308825 | cell-based format | Scientific Literature | |
| 12. | ALA4339652 | B | Negative allosteric modulation of recombinant human GluN1a/GluN2D expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced response preincubated for 5 mins followed by glutamate/glycine addition and measured after 5 mins by calcium 5 dye based FLIPR TETRA analysis | Homo sapiens | 2 | ALA4339196 | cell-based format | Scientific Literature | |
| 13. | ALA4835979 | B | Negative allosteric modulation of GluN1/GluN2D (unknown origin) expressed in HEK293 cells assessed as inhibition of current induced by NDMA and glycine at 30 uM by whole-cell patch clamp method | Homo sapiens | 1 | ALA4834434 | cell-based format | Scientific Literature | |
| 14. | ALA5132339 | B | Antagonist activity at GluN1/GluN2D NMDA receptor (unknown origin) transfected in HEK293 cells assessed as inhibition of glycine induced current response at 10 uM in presence of L-glutamate by patch-clamp method | Homo sapiens | 2 | ALA5131388 | cell-based format | Scientific Literature | |
| 15. | ALA5136766 | B | Positive allosteric modulation of recombinant human GluN1/GluN2D receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamate-induced channel current at -70 mV holding potential by whole cell patch clamp method | Homo sapiens | 1 | ALA5131569 | cell-based format | Scientific Literature | |
| 16. | ALA5136768 | B | Positive allosteric modulation of recombinant human GluN1/GluN2D receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamate-induced channel current at -70 mV holding potential by whole cell patch clamp method relative to control | Homo sapiens | 1 | ALA5131569 | cell-based format | Scientific Literature | |
| 17. | ALA5145419 | B | Positive allosteric modulator activity at GluN1a/GluN2D (unknown origin) expressed in CHO cells in presence of glutamate by Ca2+ influx assay | Homo sapiens | 1 | ALA5143566 | cell-based format | Scientific Literature | |
| 18. | ALA5145422 | B | Positive allosteric modulator activity at GluN1a/GluN2D (unknown origin) expressed in CHO cells at 30 uM in presence of glutamate by Ca2+ influx assay relative to control | Homo sapiens | 1 | ALA5143566 | cell-based format | Scientific Literature |
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