# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2389984 | B | Activation of mouse TLR4/MD-2/CD14 complex in C57BL/6 mouse BMDC cells assessed as NFkappaB activation by SEAP assay in presence of LPS-RS | Mus musculus | 1 | ALA2384907 | cell-based format | Scientific Literature | |
2. | ALA3386505 | B | Activation of human TLR4/MD2 complex in mouse RAW264.7 cells assessed as induction of NFkappaB activation incubated for 18 hrs | Mus musculus | 1 | ALA3352206 | cell-based format | Scientific Literature | |
3. | ALA4015732 | B | Binding affinity to CD14/MD2 in mouse RAW-Blue cells assessed as inhibition of LPS-induced TLR4 signaling preincubated for 30 mins followed by LPS stimulation measured after overnight incubation by secreted embryonic alkaline phosphatase reporter gene assay | Mus musculus | 2 | ALA4014316 | cell-based format | Scientific Literature | |
4. | ALA4015733 | B | Binding affinity to CD14/MD2 in Balb/c mouse splenocytes assessed as inhibition of LPS-induced TLR4-MyD88 pathway by measuring reduction in TNFalpha expression at 1 to 10 uM preincubated for 30 mins followed by LPS stimulation for 5 hrs by qRT-PCR method | Mus musculus | 2 | ALA4014316 | cell-based format | Scientific Literature |