# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2317528 | B | Inhibition of Tankyrase in human HEK293 cells assessed as inhibition of Wnt pathway by Wnt3a-induced STF assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA2330784 | B | Ratio of JW74 IC50 to compound IC50 for TNKS1/2 in HEK293 cells assessed as inhibition of Wnt/beta-casein pathway after 24 hrs by luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA2330983 | B | Inhibition of TNKS1/2 in HEK293 cells assessed as inhibition of Wnt/beta-casein pathway at 10 uM after 24 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA2330984 | B | Inhibition of TNKS1/2 in HEK293 cells assessed as inhibition of Wnt/beta-casein pathway after 24 hrs by luciferase reporter gene assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
5. | ALA2384334 | B | Inhibition of tankyrase in human SW480 cells assessed as accumulation of Axin2 after 24 hrs by Hoechst dye-based method in presence of FBA | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA2384482 | B | Inhibition of tankyrase in human SW480 cells assessed as degradation of beta catenin after 40 to 48 hrs | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
7. | ALA2384483 | B | Inhibition of tankyrase in human SW480 cells assessed as accumulation of axin2 after 24 hrs by Hoechst dye-based method | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
8. | ALA2433132 | B | Inhibition of tankyrase1/2 (unknown origin) | Homo sapiens | 2 | protein format | Scientific Literature | ||
9. | ALA3102002 | B | Inhibition of tankyrase in human DLD1 cells assessed as inhibition of Wnt gene transcription after 40 to 48 hrs by STF assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
10. | ALA3102003 | B | Inhibition of tankyrase in human SW480 cells assessed as degradation of total beta-catenin after 40 to 48 hrs | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
11. | ALA3102004 | B | Inhibition of tankyrase in human SW480 cells assessed as axin2 accumulation after 24 hrs by Hoechst dye-based assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
12. | ALA3243248 | B | Inhibition of tankyrase in human DLD1 cells assessed as inhibition of TCF-dependent transcriptional activity after 24 hrs by dual luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA3243249 | B | Inhibition of tankyrase in human DLD1 cells assessed as inhibition of TCF-dependent transcriptional activity at 1 to 20 uM after 24 hrs by dual luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA3381968 | B | Inhibition of tankyrase in human DLD1 cells assessed as reduction in Wnt activity at 10 uM after 24 hrs by TCF-luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA3382566 | B | Inhibition of tankyrase in human DLD1 cells assessed as reduction in Wnt activity after 24 hrs by TCF-luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
16. | ALA3739069 | B | Inhibition of Tankyrase in human DLD1 cells assessed as T-cell factor level after 24 hrs by luciferase reporter gene assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
17. | ALA3743848 | B | Inhibition of TNSK1/2-activated Wnt pathway in human DLD-1 TOPFlash/EF1a Renilla reporter cells after 24 hrs by Steady-Glo Luciferase assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
18. | ALA3757226 | B | Inhibition of tankyrase in human HEK293 cells assessed as decrease in non-phosphorylated beta-catenin level after 24 hrs by western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA3757229 | B | Inhibition of tankyrase in WNT3a-stimulated human HEK293 cells by luciferase reporter gene assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
20. | ALA3757230 | B | Inhibition of tankyrase in human HEK293 cells assessed as increase in AXIN1 expression after 24 hrs by western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |