| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA666035 | F | Relative antagonistic potency in vitro measuring alteration of CRF-induced release of ACTH by rat anterior pituitary cells in culture | 37 | cell-based format | Scientific Literature | |||
| 2. | ALA663562 | B | Compound was evaluated for affinity towards Corticotropin releasing factor receptor 1 expressing tissues such as Cortex, cerebellum | 2 | tissue-based format | Scientific Literature | |||
| 3. | ALA663563 | B | Affinity for the Corticotropin releasing factor receptor 1 (CRHR1) was determined in rat brain | 2 | tissue-based format | Scientific Literature | |||
| 4. | ALA663564 | B | Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 1 | Rattus norvegicus | 9 | single protein format | Scientific Literature | ||
| 5. | ALA664191 | B | Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 1; ND=Not determined | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
| 6. | ALA664192 | B | Binding affinity was determined against corticotropin releasing factor receptor 1 | 33 | single protein format | Scientific Literature | |||
| 7. | ALA664193 | B | Binding affinity was measured on rat Corticotropin releasing factor receptor 1 | 8 | single protein format | Scientific Literature | |||
| 8. | ALA664094 | B | Affinity against Corticotropin releasing factor receptor 1 | 1 | single protein format | Scientific Literature | |||
| 9. | ALA664982 | B | Inhibition of binding of 70 pM [125I]-Try0-o-Corticotropin-releasing Factor (CFR) to Corticotropin releasing hormone receptor 1 in Rat brain membrane | 5 | cell membrane format | Scientific Literature | |||
| 10. | ALA664985 | B | Binding affinity towards Corticotropin releasing hormone receptor type 1 of rat cerebellum using [125I]Tyr-sauvagine as radioligand. | 4 | tissue-based format | Scientific Literature | |||
| 11. | ALA664986 | B | Compound was tested in vitro for its ability to displace [125 I]Tyr-sauvagine from corticotropin-releasing hormone type 1 receptor in rat cerebellum | 7 | tissue-based format | Scientific Literature | |||
| 12. | ALA790468 | F | Intrinsic activity in ACTH release assay as percent CRF response | 34 | assay format | Scientific Literature | |||
| 13. | ALA830013 | B | Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1 | Rattus norvegicus | 26 | single protein format | Scientific Literature | ||
| 14. | ALA830892 | B | Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptor | Rattus norvegicus | 32 | tissue-based format | Scientific Literature | ||
| 15. | ALA830444 | F | Percent occupancy of corticotropin releasing factor receptor 1 in defensive withdrawal model in rats after oral administration; Dose 1 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA830445 | B | Percent occupancy of corticotropin releasing factor receptor 1 in defensive withdrawal model in rats after oral administration; Dose 3 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA830446 | B | Percent occupancy of corticotropin releasing factor receptor 1 in defensive withdrawal model in rats after oral administration; Dose 10 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA859232 | B | Displacement of [125I]Tyr-o-CRF from CRF1 receptor in rat frontal cortex homogenates | Rattus norvegicus | 24 | tissue-based format | Scientific Literature | ||
| 19. | ALA918439 | B | Displacement of [125I]Tyr-o-CRF from CRF1 receptor in rat frontal cortex homogenates | Rattus norvegicus | 20 | tissue-based format | Scientific Literature | ||
| 20. | ALA2061535 | F | Antagonist activity at rat CFR1R | Rattus norvegicus | 43 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!