# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA666040 | B | Compound was tested for the binding affinity to human corticotropin releasing factor receptor (hCRF2) | 1 | ALA1132922 | single protein format | Scientific Literature | ||
2. | ALA665760 | F | Effective concentration against Corticotropin releasing factor receptor 2 in IMR-32 cells | 1 | ALA1136357 | cell-based format | Scientific Literature | ||
3. | ALA665761 | B | Binding affinity of compound towards human Corticotropin releasing factor receptor 2; inactive at 10 uM | 1 | ALA1138825 | single protein format | Scientific Literature | ||
4. | ALA665762 | B | Binding affinity towards human Corticotropin releasing factor receptor 2 by the displacement of [125I]CRF from CHO cells; IA means Inactive | 2 | ALA1147540 | cell-based format | Scientific Literature | ||
5. | ALA664976 | B | Inhibitory activity against Corticotropin releasing factor receptor 2 | 1 | ALA1136357 | single protein format | Scientific Literature | ||
6. | ALA664980 | F | Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu1,Nle17]-sauvagine as radioligand | 28 | ALA1135628 | assay format | Scientific Literature | ||
7. | ALA843662 | F | Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assay | 5 | ALA1132922 | assay format | Scientific Literature | ||
8. | ALA881337 | B | Binding affinity of the receptor h-CRF2-alpha with peptidic agonists | 5 | ALA1132922 | single protein format | Scientific Literature | ||
9. | ALA827397 | B | Binding affinity for human Corticotropin releasing factor receptor 2 | Homo sapiens | 1 | ALA1142705 | single protein format | Scientific Literature | |
10. | ALA831869 | B | Inhibition of [125I]- sauvagine binding to corticotropin releasing factor receptor 2 of porcine choroid plexus | Sus scrofa | 2 | ALA1138750 | single protein format | Scientific Literature | |
11. | ALA934307 | B | Binding affinity for human CRF2 receptor | Homo sapiens | 1 | ALA1141603 | single protein format | Scientific Literature | |
12. | ALA1004668 | F | Antagonist activity at human CRF2 receptor expressed in CHO cells assessed as effect on sauvagine-induced cAMP production | Homo sapiens | 1 | ALA1140209 | cell-based format | Scientific Literature | |
13. | ALA994500 | B | Displacement of [125I]Tyr0-sauvagine from CRF2beta receptor expressed in pig choroid plexus membrane | 1 | ALA1138476 | cell membrane format | Scientific Literature | ||
14. | ALA985702 | B | Binding affinity to human CRF2alpha receptor | Homo sapiens | 4 | ALA1138477 | single protein format | Scientific Literature | |
15. | ALA985718 | F | Antagonist activity at human cloned CRF2alpha receptor expressed in HEK293 cells | Homo sapiens | 4 | ALA1138477 | cell-based format | Scientific Literature | |
16. | ALA985719 | F | Agonist activity at human cloned CRF2alpha receptor expressed in HEK293 cells | Homo sapiens | 4 | ALA1138477 | cell-based format | Scientific Literature | |
17. | ALA1247746 | B | Binding affinity to human recombinant CRF2alpha receptor | Homo sapiens | 1 | ALA1240532 | single protein format | Scientific Literature | |
18. | ALA2089418 | F | Antagonist activity at human CRF2 receptor expressed in IMR32 cells assessed as inhibition of CRF-stimulated cAMP accumulation | Homo sapiens | 1 | ALA2086316 | cell-based format | Scientific Literature | |
19. | ALA2187016 | F | Antagonist activity at human CRF2 receptor assessed as inhibition of CRF-induced intracellular cAMP accumulation | Homo sapiens | 1 | ALA2177001 | cell-based format | Scientific Literature | |
20. | ALA3631937 | B | Displacement of [125I]-antisauvagine-30 from human CRF2 receptor expressed in HEK293T cells at 1 uM after 2 hrs by scintillation counting | Homo sapiens | 17 | ALA3627705 | cell-based format | Scientific Literature |