# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3362659 | Functional | Agonist activity against human GPR39 expressed in CHO cells by BacMam IP1 HTRF/summary (Abse5) assay | Homo sapiens | 1 | ALA3351646 | cell-based format | Scientific Literature | |
2. | ALA3384902 | Functional | Agonist activity at human GPR39 by IP1 assay | Homo sapiens | 3 | ALA3352269 | single protein format | Scientific Literature | |
3. | ALA3384907 | Functional | Agonist activity at human GPR39 expressed in HEK293 cells by IP1 assay | Homo sapiens | 22 | ALA3352269 | cell-based format | Scientific Literature | |
4. | ALA3385496 | Functional | Agonist activity at human GPR39 expressed in HEK293 cells by cAMP assay | Homo sapiens | 5 | ALA3352269 | cell-based format | Scientific Literature | |
5. | ALA3385497 | Functional | Agonist activity at human GPR39 expressed in HEK293 cells by cAMP assay relative to forskolin | Homo sapiens | 5 | ALA3352269 | cell-based format | Scientific Literature | |
6. | ALA3385508 | Functional | Agonist activity at human GPR39 expressed in HEK293 cells in presence of sub-EC50 dose of zinc chloride by IP1 assay | Homo sapiens | 1 | ALA3352269 | cell-based format | Scientific Literature | |
7. | ALA3096567 | Functional | Agonist activity at GPR39 in human HT-29 cells assessed as cAMP accumulation up to 30 uM | Homo sapiens | 2 | ALA3091456 | cell-based format | Scientific Literature | |
8. | ALA3096568 | Functional | Agonist activity at GPR39 in human HT-29 cells assessed as intracellular Ca2+ mobilization up to 30 uM after 72 hrs by FLIPR assay | Homo sapiens | 2 | ALA3091456 | cell-based format | Scientific Literature | |
9. | ALA3096571 | Binding | Agonist activity at GPR39 in human islets assessed as 11.2 mM glucose-stimulated insulin secretion up to 10 uM after 1 hr | Homo sapiens | 1 | ALA3091456 | single protein format | Scientific Literature | |
10. | ALA3096572 | Binding | Agonist activity at GPR39 in human islets assessed as 2.8 mM glucose-stimulated insulin secretion up to 10 uM after 0.75 hrs | Homo sapiens | 1 | ALA3091456 | single protein format | Scientific Literature | |
11. | ALA3096573 | Functional | Agonist activity at GPR39 in human HT-29 cells assessed as cAMP accumulation | Homo sapiens | 1 | ALA3091456 | cell-based format | Scientific Literature | |
12. | ALA3096574 | Functional | Agonist activity at GPR39 in human HT-29 cells assessed as intracellular Ca2+ mobilization after 72 hrs by FLIPR assay in presence of siRNA | Homo sapiens | 1 | ALA3091456 | cell-based format | Scientific Literature | |
13. | ALA3096575 | Functional | Agonist activity at GPR39 in human HT-29 cells assessed as increase in intracellular Ca2+ mobilization after 72 hrs by FLIPR assay | Homo sapiens | 1 | ALA3091456 | cell-based format | Scientific Literature | |
14. | ALA3096578 | Functional | Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced cAMP production preincubated for 30 mins measured after 60 mins relative to Zn+2 | Homo sapiens | 4 | ALA3091456 | cell-based format | Scientific Literature | |
15. | ALA3096579 | Binding | Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced intracellular Ca+2 mobilization after 1 hr by Fluo-4 No staining-based FLIPR assay relative to Zn+2 | Homo sapiens | 4 | ALA3091456 | cell-based format | Scientific Literature | |
16. | ALA3096580 | Functional | Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced cAMP production preincubated for 30 mins measured after 60 mins | Homo sapiens | 4 | ALA3091456 | cell-based format | Scientific Literature | |
17. | ALA3096582 | Binding | Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced intracellular Ca+2 mobilization after 1 hr by Fluo-4 No staining-based FLIPR assay | Homo sapiens | 4 | ALA3091456 | cell-based format | Scientific Literature | |
18. | ALA3995517 | Functional | Agonist activity at human GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation measured after 75 mins by scintillation proximity assay | Homo sapiens | 38 | ALA3994609 | cell-based format | Scientific Literature | |
19. | ALA3995518 | Functional | Agonist activity at human GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation in presence of 100 nM Zn2+ measured after 75 mins by scintillation proximity assay | Homo sapiens | 5 | ALA3994609 | cell-based format | Scientific Literature | |
20. | ALA3995519 | Functional | Agonist activity at human GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation in presence of 10 uM Zn2+ measured after 75 mins by scintillation proximity assay | Homo sapiens | 38 | ALA3994609 | cell-based format | Scientific Literature |