| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3096567 | F | Agonist activity at GPR39 in human HT-29 cells assessed as cAMP accumulation up to 30 uM | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA3096568 | F | Agonist activity at GPR39 in human HT-29 cells assessed as intracellular Ca2+ mobilization up to 30 uM after 72 hrs by FLIPR assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA3096571 | B | Agonist activity at GPR39 in human islets assessed as 11.2 mM glucose-stimulated insulin secretion up to 10 uM after 1 hr | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA3096572 | B | Agonist activity at GPR39 in human islets assessed as 2.8 mM glucose-stimulated insulin secretion up to 10 uM after 0.75 hrs | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA3096573 | F | Agonist activity at GPR39 in human HT-29 cells assessed as cAMP accumulation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3096574 | F | Agonist activity at GPR39 in human HT-29 cells assessed as intracellular Ca2+ mobilization after 72 hrs by FLIPR assay in presence of siRNA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3096575 | F | Agonist activity at GPR39 in human HT-29 cells assessed as increase in intracellular Ca2+ mobilization after 72 hrs by FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3096578 | F | Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced cAMP production preincubated for 30 mins measured after 60 mins relative to Zn+2 | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA3096579 | B | Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced intracellular Ca+2 mobilization after 1 hr by Fluo-4 No staining-based FLIPR assay relative to Zn+2 | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA3096580 | F | Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced cAMP production preincubated for 30 mins measured after 60 mins | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA3096582 | B | Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced intracellular Ca+2 mobilization after 1 hr by Fluo-4 No staining-based FLIPR assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA3384902 | F | Agonist activity at human GPR39 by IP1 assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA3384907 | F | Agonist activity at human GPR39 expressed in HEK293 cells by IP1 assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 14. | ALA3385496 | F | Agonist activity at human GPR39 expressed in HEK293 cells by cAMP assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 15. | ALA3385497 | F | Agonist activity at human GPR39 expressed in HEK293 cells by cAMP assay relative to forskolin | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 16. | ALA3385508 | F | Agonist activity at human GPR39 expressed in HEK293 cells in presence of sub-EC50 dose of zinc chloride by IP1 assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3362659 | F | Agonist activity against human GPR39 expressed in CHO cells by BacMam IP1 HTRF/summary (Abse5) assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3995517 | F | Agonist activity at human GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation measured after 75 mins by scintillation proximity assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
| 19. | ALA3995518 | F | Agonist activity at human GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation in presence of 100 nM Zn2+ measured after 75 mins by scintillation proximity assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 20. | ALA3995519 | F | Agonist activity at human GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation in presence of 10 uM Zn2+ measured after 75 mins by scintillation proximity assay | Homo sapiens | 38 | cell-based format | Scientific Literature |
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