# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3110796 | B | Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substrate assessed as enzyme-substrate-inhibitor complex by Dixon reciprocal plot analysis | Leishmania amazonensis | 3 | ALA3108701 | assay format | Scientific Literature | |
2. | ALA3110797 | B | Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substrate by Dixon reciprocal plot analysis | Leishmania amazonensis | 6 | ALA3108701 | assay format | Scientific Literature | |
3. | ALA3110798 | B | Inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substrate incubated for 10 mins prior to substrate addition measured after 10 mins by colorimetry | Leishmania amazonensis | 18 | ALA3108701 | assay format | Scientific Literature | |
4. | ALA4342347 | B | Non-competitive inhibition of Leishmania amazonensis arginase using L-arginine as substrate incubated for 15 mins | Leishmania amazonensis | 1 | ALA4340573 | single protein format | Scientific Literature | |
5. | ALA4342348 | B | Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli at 100 uM using L-arginine as substrate relative to control | Leishmania amazonensis | 7 | ALA4340573 | assay format | Scientific Literature | |
6. | ALA4342349 | B | Competitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using 25 to 100 mM L-arginine levels | Leishmania amazonensis | 2 | ALA4340573 | assay format | Scientific Literature | |
7. | ALA4342350 | B | Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate | Leishmania amazonensis | 7 | ALA4340573 | assay format | Scientific Literature | |
8. | ALA4342351 | B | Uncompetitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as dissociation constant for ternary complex enzyme-substrate-inhibitor using L-arginine as substrate by Dixon or Cornish-Bowden plot analysis | Leishmania amazonensis | 7 | ALA4340573 | assay format | Scientific Literature | |
9. | ALA4387398 | B | Competitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measuring dissociation constant for enzyme-inhibitor complex using L-arginine as substrate by Berthelot colorimetric method based Dixon/Cornish-Bowden plot analysis relative to control | Leishmania amazonensis | 10 | ALA4385644 | assay format | Scientific Literature | |
10. | ALA4387399 | B | Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production using L-arginine as substrate by Berthelot colorimetric method relative to control | Leishmania amazonensis | 10 | ALA4385644 | assay format | Scientific Literature | |
11. | ALA4387400 | B | Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production at 100 uM using L-arginine as substrate by Berthelot colorimetric method relative to control | Leishmania amazonensis | 8 | ALA4385644 | assay format | Scientific Literature | |
12. | ALA4387401 | B | Mixed type inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measuring dissociation constant for enzyme-substrate-inhibitor complex using L-arginine as substrate by Berthelot colorimetric method based Dixon/Cornish-Bowden plot analysis relative to control | Leishmania amazonensis | 10 | ALA4385644 | assay format | Scientific Literature | |
13. | ALA4387404 | B | Ratio of Ki to Kis for inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production using L-arginine as substrate by Berthelot colorimetric method based Dixon/Cornish-Bowden plot analysis relative to control | Leishmania amazonensis | 1 | ALA4385644 | assay format | Scientific Literature | |
14. | ALA4428368 | B | Competitive inhibition of Leishmania amazonensis arginase assessed as inhibition constant for enzyme-inhibitor complex using L-arginine as substrate incubated for 15 mins by Dixon plot analysis | Leishmania amazonensis | 1 | ALA4428031 | single protein format | Scientific Literature |