| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3111123 | B | Displacement of H3K14(Ac) peptide from TIF1alpha bromodomain (unknown origin) at 50 uM by AlphaScreen assay relative to control | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 2. | ALA3111124 | B | Displacement of H3K14(Ac) peptide from TIF1alpha bromodomain (unknown origin) at 100 uM by AlphaScreen assay relative to control | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 3. | ALA3111330 | B | Displacement of H3K14(Ac) peptide from TIF1alpha bromodomain (unknown origin) by AlphaScreen assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 4. | ALA3111498 | B | Binding affinity to TIF1alpha bromodomain (unknown origin) assessed as change in melting temperature at 10 uM by differential scanning fluorimetric analysis | Homo sapiens | 35 | single protein format | Scientific Literature | ||
| 5. | ALA3134631 | B | Binding affinity to TIF1 (unknown origin) at 4 uM by thermal shift assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA3226587 | B | Binding affinity to TIF1alpha bromodomain (unknown origin) assessed as change in melting temperature at 10 uM by differential scanning fluorimetric analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3383432 | B | Inhibition of human TIF1alpha bromodomain by BROMOscan assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3383433 | B | Inhibition of human TIF1alpha PHD/bromodomain by BROMOscan assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA3583520 | B | Binding affinity to biotinylated TRIM24 (790 to 972 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometry method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3773285 | B | Binding affinity to biotinylated TIF1 bromodomain-1 (unknown origin) expressed in Escherichia coli at 0.2 to 1 uM by Biolayer Interferometric analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 11. | ALA3771488 | B | Inhibition of N-terminal His6-SUMO-1-tagged recombinant human TRIM24 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by Alpha Screen assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 12. | ALA3771491 | B | Binding affinity to N-terminal His6-SUMO-1-tagged recombinant human TRIM24 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3771496 | B | Binding affinity to N-terminal His6-SUMO-1-tagged wild type human TRIM24 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells assessed as reduction of fluorescent recovery half time at 1 uM by FRAP assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3771497 | B | Binding affinity to human TRIM24 bromodomain N980F mutant expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells assessed as reduction of fluorescent recovery half time by FRAP assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3779310 | B | Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (1 to 33 residues) peptide after 1 hr by AlphaScreen assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
| 16. | ALA3779314 | B | Inhibition of Flag-tagged TRIM24-PHD/bromodomain (unknown origin) expressed in human HeLa cells for 2 hrs by AlphaLisa assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 17. | ALA3779317 | B | Ratio of EC50 for Flag-tagged TRIM24-PHD/bromodomain (unknown origin) expressed in human HeLa cells to IC50 for recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 18. | ALA3779318 | B | Binding affinity to recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3779320 | B | Binding affinity to recombinant human TRIM24-PHD/bromodomain expressed in bacterial system by bromoscan assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA3777044 | B | Inhibition of recombinant human TRIM33 PHD/bromodomain expressed in bacterial system assessed as residual activity at 1 uM by bromoscan assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature |
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