# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3111339 | B | Binding affinity to TAF1L bromodomain-2 (unknown origin) assessed as change in melting temperature at 10 uM by differential scanning fluorimetric analysis | Homo sapiens | 35 | ALA3108763 | single protein format | Scientific Literature | |
2. | ALA3383431 | B | Inhibition of human TAF1L by BROMOscan assay | Homo sapiens | 1 | ALA3351476 | single protein format | Scientific Literature | |
3. | ALA3380073 | B | Binding affinity to TAF1L (unknown origin) by bromodomain displacement assay | Homo sapiens | 1 | ALA3351605 | single protein format | Scientific Literature | |
4. | ALA3591378 | B | Binding affinity to TAF1L (unknown origin) by BROMOscan panel based assay | Homo sapiens | 1 | ALA3588744 | single protein format | Scientific Literature | |
5. | ALA3772747 | B | Binding affinity to recombinant human TAF1L bromodomain-2 assessed as melting temperature shift at 10 uM by real time PCR analysis | Homo sapiens | 1 | ALA3769341 | single protein format | Scientific Literature | |
6. | ALA3772748 | B | Binding affinity to biotinylated C-terminal Avi/His-TEV-fused TAF1L bromodomain-2 (unknown origin) expressed in Escherichia coli by isothermal titration calorimetric analysis | Homo sapiens | 1 | ALA3769341 | assay format | Scientific Literature | |
7. | ALA3773283 | B | Binding affinity to biotinylated TAF1L bromodomain-1 (unknown origin) expressed in Escherichia coli at 0.2 to 1 uM by Biolayer Interferometric analysis | Homo sapiens | 2 | ALA3769341 | assay format | Scientific Literature | |
8. | ALA3773284 | B | Binding affinity to biotinylated TAF1L bromodomain-2 (unknown origin) expressed in Escherichia coli at 0.2 to 1 uM by Biolayer Interferometric analysis | Homo sapiens | 2 | ALA3769341 | assay format | Scientific Literature | |
9. | ALA3777043 | B | Inhibition of recombinant human TAF1L bromodomain 2 expressed in bacterial system assessed as residual activity at 1 uM by bromoscan assay relative to control | Homo sapiens | 1 | ALA3774340 | assay format | Scientific Literature | |
10. | ALA3863022 | B | Binding affinity to TAF1L bromodomain 1 (unknown origin) assessed as change in melting temperature at 100 uM by differential scanning fluorimetric assay | Homo sapiens | 1 | ALA3861991 | single protein format | Scientific Literature | |
11. | ALA3863023 | B | Binding affinity to TAF1L bromodomain 2 (unknown origin) assessed as change in melting temperature at 100 uM by differential scanning fluorimetric assay | Homo sapiens | 1 | ALA3861991 | single protein format | Scientific Literature | |
12. | ALA4020269 | B | Binding affinity to human TAF1L (2) (Q1523 to D1654 residues) expressed in bacterial expression system by BROMOscan assay | Homo sapiens | 1 | ALA4017535 | assay format | Scientific Literature | |
13. | ALA4038411 | B | Inhibition of human TAF1L (Q1523 to D1654 residues) expressed in bacterial expression system by BROMOscan assay | Homo sapiens | 2 | ALA4038268 | assay format | Scientific Literature | |
14. | ALA4047557 | B | Inhibition of human partial length TAF1L BD2 (Q1523 to D1654 residues) expressed in bacterial expression system assessed as residual activity at 500 nM relative to control by BROMOscan assay | Homo sapiens | 1 | ALA4043246 | assay format | Scientific Literature | |
15. | ALA4051535 | B | Inhibition of human GST-tagged TAF1L BD2 (1517 to 1649 residues) expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra-acetylated histone H4 (1 to 20 residues) peptide as substrate measured after 1 hr by TR-FRET assay | Homo sapiens | 3 | ALA4049437 | assay format | Scientific Literature | |
16. | ALA4051584 | B | Inhibition of TAF1L BD1 (unknown origin) assessed as change in melting temperature at 10 uM by SYPRO Orange-dye based fluorescence thermal shift assay | Homo sapiens | 1 | ALA4049437 | single protein format | Scientific Literature | |
17. | ALA4051585 | B | Inhibition of TAF1L BD2 (unknown origin) assessed as change in melting temperature at 10 uM by SYPRO Orange-dye based fluorescence thermal shift assay | Homo sapiens | 1 | ALA4049437 | single protein format | Scientific Literature | |
18. | ALA4051591 | B | Stabilization of human GST-tagged TAF1L BD2 (1517 to 1649 residues) expressed in Escherichia coli BL21 (DE3) at 10 uM by SYPRO Orange-dye based fluorescence thermal shift assay | Homo sapiens | 1 | ALA4049437 | assay format | Scientific Literature | |
19. | ALA4051609 | B | Binding affinity to human GST-tagged TAF1L BD2 (1517 to 1649 residues) expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 by ITC | Homo sapiens | 1 | ALA4049437 | assay format | Scientific Literature | |
20. | ALA4058272 | B | Binding affinity to human DNA-tagged TAF1L bromodomain 2 (1523 to 1654 residues) expressed in bacterial expression system by BROMOscan assay | Homo sapiens | 1 | ALA4052791 | assay format | Scientific Literature |