| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3111726 | B | Inhibition of WHSC1L (unknown origin)-mediated incorporation of methyl group from [3H]-SAM into peptide substrate up to 50 uM after 1 hr by scintillation proximity assay | Homo sapiens | 1 | ALA3108684 | single protein format | Scientific Literature | |
| 2. | ALA3592413 | B | Inhibition of NSD3 (unknown origin) at 1 uM after 1 hr by filter-based assay | Homo sapiens | 1 | ALA3588844 | single protein format | Scientific Literature | |
| 3. | ALA3784091 | B | Inhibition of human NSD3 at 10 and 50 uM | Homo sapiens | 1 | ALA3779843 | single protein format | Scientific Literature | |
| 4. | ALA3803387 | B | Inhibition of WHSC1L1 (unknown origin) at 10 uM relative to control | Homo sapiens | 2 | ALA3797202 | single protein format | Scientific Literature | |
| 5. | ALA3821916 | B | Inhibition of NSD3 (unknown origin) at 1 to 50 uM by TCA precipitation assay | Homo sapiens | 1 | ALA3817823 | single protein format | Scientific Literature | |
| 6. | ALA3859064 | B | Inhibition of NSD3 (unknown origin) at 50 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by scintillation proximity assay | Homo sapiens | 1 | ALA3856251 | single protein format | Scientific Literature | |
| 7. | ALA4346640 | B | Inhibition of NSD3 (unknown origin) at 10 uM using [3H-SAM] and nucleosome as substrate incubated for 1 hr by scintillation proximity assay | Homo sapiens | 1 | ALA4342528 | single protein format | Scientific Literature | |
| 8. | ALA4377329 | B | Inhibition of human NSD3 up to 50 uM using chicken nucleosome as substrate and in presence of [3H]-SAM incubated for 1 hr by filter-based assay | Homo sapiens | 1 | ALA4376809 | single protein format | Scientific Literature | |
| 9. | ALA4411216 | B | Inhibition of NSD3 (unknown origin) at <5 uM using histone H3 peptide (1 to 45) as substrate in presence of co-factor SAM by LC-MS analysis | Homo sapiens | 1 | ALA4406923 | single protein format | Scientific Literature | |
| 10. | ALA4480240 | B | Inhibition of NSD3 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
| 11. | ALA4705999 | B | Binding affinity to NSD3 PWWP1 domain (263 to 398 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) by SPR method | Homo sapiens | 2 | ALA4699657 | assay format | Scientific Literature | |
| 12. | ALA4736940 | B | Binding affinity to NSD3 PWWP1 domain (unknown origin) assessed as aggregation temperature at 400 uM by heating at 25 to 85 degC by differential static light scattering method | Homo sapiens | 1 | ALA4732170 | single protein format | Scientific Literature | |
| 13. | ALA4736945 | B | Displacement of Halo-tagged Histone H3.3 from Nanoluc-tagged NSD3- PWWP1 (unknown origin) transfected in human U2OS cells at 3 to 50 uM preincubated for one day followed by Nano-GloR substrate addition at the next day and measured withing 10 mins by NanoBRET assay | Homo sapiens | 1 | ALA4732170 | cell-based format | Scientific Literature | |
| 14. | ALA4827269 | B | Inhibition of human NSD3-SET using histone H3.1 as substrate incubated for 1 hr by Western blot analysis | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
| 15. | ALA5030820 | B | Inhibition of NSD3 (unknown origin) at 1 to 10 uM | Homo sapiens | 2 | ALA5030506 | single protein format | Scientific Literature | |
| 16. | ALA5119842 | B | Inhibition of human recombinant N-terminal GST-tagged NSD3 (1021 to 1322 residues) expressed in Escherichia coli at 10 uM using DNA as substrate by scintillation/filter assay | Homo sapiens | 1 | ALA5113528 | assay format | Scientific Literature | |
| 17. | ALA5119879 | B | Inhibition of human recombinant N-terminal GST-tagged NSD3 (1021 to 1322 residues) expressed in Escherichia coli at 50 uM using DNA as substrate by scintillation/filter assay relative to control | Homo sapiens | 1 | ALA5113528 | assay format | Scientific Literature | |
| 18. | ALA5124715 | B | Binding affinity to NSD3 (unknown origin) assessed as dissociation constant | Homo sapiens | 1 | ALA5120900 | single protein format | Scientific Literature | |
| 19. | ALA5124716 | B | Inhibition of GST-tagged NSD3-PWWP1 domain (247 to 398 residues) (unknown origin) by TR-FRET assay | Homo sapiens | 1 | ALA5120900 | single protein format | Scientific Literature | |
| 20. | ALA5129696 | B | Inhibition of N-terminal GST tagged NSD3 (1021 to 1322 residues) (unknown origin) expressed in Escherichia coli at 1 uM using 3H-SAM as a substrate relative to control | Homo sapiens | 1 | ALA5126600 | assay format | Scientific Literature |
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