| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3111956 | B | Inhibition of NEK10 (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control | Homo sapiens | 1 | ALA3108735 | single protein format | Scientific Literature | |
| 2. | ALA4025269 | B | Inhibition of wild-type human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
| 3. | ALA4044080 | B | Inhibition of wild-type human partial length NEK10 (L488 to R809 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
| 4. | ALA4157159 | B | Binding affinity to wild-type human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4152344 | assay format | Scientific Literature | |
| 5. | ALA4185938 | B | Binding affinity to wild-type human partial length NEK10 (L488 to R809 residues) expressed in HEK293 cells at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4184148 | cell-based format | Scientific Literature | |
| 6. | ALA4230838 | B | Binding affinity to wild-type human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4229344 | assay format | Scientific Literature | |
| 7. | ALA4264427 | B | Binding affinity to wild-type human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system assessed as remaining unbound target protein level at 1000 nM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4261600 | assay format | Scientific Literature | |
| 8. | ALA4307937 | B | Binding affinity to wild-type human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system assessed as residual binding level at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4304811 | assay format | Scientific Literature | |
| 9. | ALA4358016 | B | Binding affinity to wild-type human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4354843 | assay format | Scientific Literature | |
| 10. | ALA4365854 | B | Inhibition of wild-type human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system assessed as residual activity at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4364269 | assay format | Scientific Literature | |
| 11. | ALA4382647 | B | Binding affinity to wild-type human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4382192 | assay format | Scientific Literature | |
| 12. | ALA4389366 | B | Inhibition of wild-type human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4387741 | assay format | Scientific Literature | |
| 13. | ALA4389843 | B | Inhibition of wild-type human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4387741 | assay format | Scientific Literature | |
| 14. | ALA4391469 | B | Binding affinity to wild-type human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system assessed as residual binding level at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4390652 | assay format | Scientific Literature | |
| 15. | ALA4408774 | B | Binding affinity to NEK10 (unknown origin) | Homo sapiens | 1 | ALA4406837 | single protein format | Scientific Literature | |
| 16. | ALA4737635 | B | Inhibition of human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system assessed as residual activity at 10 uM by kinome scan method relative to control | Homo sapiens | 1 | ALA4732196 | assay format | Scientific Literature | |
| 17. | ALA4805051 | B | Inhibition of human NEK10 assessed as percent of control at 2000 nM by KINOMEscan assay relative to control | Homo sapiens | 1 | ALA4804282 | single protein format | Patent Bioactivity Data | |
| 18. | ALA4805639 | B | Inhibition of human NEK10 assessed as percent of control at 1000 nM by KINOMEscan assay relative to control | Homo sapiens | 1 | ALA4804283 | single protein format | Patent Bioactivity Data | |
| 19. | ALA4806656 | B | Inhibition of human NEK10 assessed as percent of control at 2000 nM by KINOMEscan assay relative to control | Homo sapiens | 1 | ALA4804286 | single protein format | Patent Bioactivity Data | |
| 20. | ALA4827587 | B | Inhibition of wild-type human partial length NEK10 (L488 to R809 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4825714 | assay format | Scientific Literature |
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