| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3119202 | B | Inhibition of PCA-1 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA3119217 | B | Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate at 10 mM after 1 hr by RT-PCR analysis | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 3. | ALA3119218 | B | Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysis | Homo sapiens | 49 | single protein format | Scientific Literature | ||
| 4. | ALA4234810 | B | Inhibition of recombinant human AlkBH3 assessed as reduction in formaldehyde release using 40-mer single N3-meC as substrate incubated for 60 mins followed by substrate addition measured after 15 mins by fluorescence assay | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 5. | ALA4234811 | B | Inhibition of recombinant human AlkBH3 assessed as reduction in formaldehyde release at 50 uM using 40-mer single N3-meC as substrate incubated for 60 mins followed by substrate addition measured after 15 mins by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA4234812 | B | Binding affinity to recombinant human AlkBH3 at 12 uM after 1 hr by far-UV circular dichroism spectroscopy | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4234813 | B | Binding affinity to recombinant human AlkBH3 at 12 uM after 1 hr by near-UV circular dichroism spectroscopy | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4234814 | B | Binding affinity to recombinant human AlkBH3 incubated for 2 mins by isothermal titration calorimetric method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4234815 | B | Competitive inhibition of recombinant human AlkBH3 assessed as reduction in formaldehyde release at 50 to 500 uM using 40-mer internal N3me-oligo-dC as substrate incubated for 60 mins followed by substrate addition measured after 15 mins by Lineweaver-Burk plot analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4234816 | B | Mixed type inhibition of recombinant human AlkBH3 assessed as reduction in formaldehyde release at 50 to 500 uM using varying levels of 2OG as substrate incubated for 60 mins followed by substrate addition measured after 15 mins by Lineweaver-Burk plot analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4234820 | B | Inhibition of AlkBH3 in human A549 cells assessed as increase in MMS-induced cytotoxicity at 1 uM after 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA5115881 | B | Inhibition of human full lenth N-terminal His6-tagged ALKBH3 (1 to 286 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5229113 | B | Inhibition of human ALKBH3 using ss-m1A DNA as substrate by HPLC analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 14. | ALA5229119 | B | Inhibition of N-terminal His-tagged human ALKBH3 (1 to 286 residues) using m6A-ssDNA as substrate incubated for 30 mins by MALDI-TOF-MS analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 15. | ALA5229151 | B | Inhibition of human ALKBH3 expressed in Escherichia coli BL21 (DE3) Rosetta cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 16. | ALA5229158 | B | Inhibition of human ALKBH3 by HPLC analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA5229160 | B | Inhibition of human ALKBH3 demethylase activity by restriction endonuclease digestion assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA5229168 | B | Inhibition of ALKBH3 (unknown origin) using 3-methyl cytosine oligo DNA as substrate incubated for 1 hr by SYBR green dye based RT-PCR analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5229169 | B | Inhibition of ALKBH3 (unknown origin) at 50 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |
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