# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3124277 | Binding | Inhibition of mitochondrial RNA polymerase (unknown origin) assessed as inhibition of single nucleotide incorporation | Homo sapiens | 4 | ALA3120104 | single protein format | Scientific Literature | |
2. | ALA3418699 | Binding | Inhibition of human mitochondrial RNA polymerase assessed as 13-mer product using [33P]RNA/DNA primer/templates used by agarose gel electrophoresis | Homo sapiens | 8 | ALA3414561 | single protein format | Scientific Literature | |
3. | ALA3418700 | Binding | Binding affinity to human mitochondrial RNA polymerase assessed as compound incorporation using [33P]RNA/DNA primer/templates used by agarose gel electrophoresis | Homo sapiens | 5 | ALA3414561 | single protein format | Scientific Literature | |
4. | ALA3428607 | Binding | Inhibition of human mitochondrial RNA polymerase using 5'-32P-R12/D18 as RNA/DNA template assessed as single nucleotide incorporation rate at 500 uM after 0.17 to 30 mins by PAGE analysis | Homo sapiens | 16 | ALA3425402 | single protein format | Scientific Literature | |
5. | ALA3796114 | Binding | Activity at human mitochondrial RNA polymerase assessed as compound incorporation into RNA up to 100 uM relative to ATP | Homo sapiens | 1 | ALA3792308 | single protein format | Scientific Literature | |
6. | ALA4008258 | ADME | Inhibition of human mitochondrial RNA polymerase after 30 mins in presence of [33P]GTP | Homo sapiens | 1 | ALA4007399 | single protein format | Scientific Literature | |
7. | ALA4008263 | ADME | Inhibition of human mitochondrial RNA polymerase assessed as single nucleotide incorporation rate in presence of 5'-[32P]-R12/D18 as primer/template by PAGE based phosphorimaging assay | Homo sapiens | 1 | ALA4007399 | single protein format | Scientific Literature | |
8. | ALA4017350 | Binding | Inhibition of human POLRMT using 5'-P32-RNA/DNA hybrid assessed as incorporation of UTP at 100 uM after 2 hrs by scintillation counting method relative to control | Homo sapiens | 2 | ALA4014354 | single protein format | Scientific Literature | |
9. | ALA4046679 | Binding | Inhibition of human mitochondrial RNA polymerase | Homo sapiens | 1 | ALA4043192 | single protein format | Scientific Literature | |
10. | ALA4123976 | ADME | Inhibition of human POLRMT assessed as single nucleotide incorporation rate at 500 uM relative to ATP | Homo sapiens | 1 | ALA4118212 | single protein format | Scientific Literature | |
11. | ALA4123979 | ADME | Inhibition of human full length POLRMT using 32P-RNA primer/DNA template assessed as single nucleotide incorporation rate at 500 uM by SDS-PAGE analysis relative to CTP | Homo sapiens | 1 | ALA4118212 | single protein format | Scientific Literature | |
12. | ALA4123983 | ADME | Inhibition of human POLRMT using 5'-FAM labelled RNA primer/DNA template duplex assessed as single nucleotide incorporation rate at 500 uM after 5 mins by SDS-PAGE analysis relative to control | Homo sapiens | 9 | ALA4118212 | single protein format | Scientific Literature | |
13. | ALA4394399 | ADME | Inhibition of human mitochondrial DNA-dependent RNA polymerase activity at 100 uM using 33P-RNA/DNA primer/template by phosphor-imaging analysis | Homo sapiens | 4 | ALA4393666 | single protein format | Scientific Literature | |
14. | ALA4413708 | ADME | Substrate activity at human POLRMT assessed as 5-radiolabled RNA/DNA incorporation levels at 100 uM after 2 hrs by PAGE analysis | Homo sapiens | 3 | ALA4411318 | single protein format | Scientific Literature |