#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3131105	B	Binding affinity to GP130 (unknown origin) by surface plasmon resonance analysis	Homo sapiens	1		single protein format	Scientific Literature
2.	ALA3131112	B	Binding affinity to GP130 in human RH30 cells assessed as protection against pronase-induced cleavage at 100 to 1000 uM preincubated for 1 hr followed by pronase induction measured after 30 mins by DARTS assay	Homo sapiens	2		cell-based format	Scientific Literature
3.	ALA3768044	B	Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gene assay	Homo sapiens	15		cell-based format	Scientific Literature
4.	ALA3768046	B	Binding affinity to wild-type gp130 (unknown origin) at 0.19 to 200 uM by surface plasmon resonance analysis	Homo sapiens	1		single protein format	Scientific Literature
5.	ALA4388697	B	Inhibition of IL-6-induced gp130 phosphorylation in human U266 cells at 10 and 20 uM pre-incubated for 1 hr before IL-6 stimulation for 10 to 15 mins by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
6.	ALA4687111	B	Binding affinity to immobilized GP130 (unknown origin) assessed as response unit at 20 uM by SPR analysis	Homo sapiens	27		single protein format	Scientific Literature
7.	ALA4687112	B	Binding affinity to immobilized GP130 (unknown origin) by SPR analysis	Homo sapiens	2		single protein format	Scientific Literature
8.	ALA4687113	B	Binding affinity to GP130 in human A549 cell lysates assessed as decrease in pronase mediated protein degradation by measuring increase in abundance of GP130 band at 100 to 1000 uM preincubated for 1 hr followed by pronase addition for 30 mins by DARTS assay	Homo sapiens	1		subcellular format	Scientific Literature
9.	ALA4687114	B	Binding affinity to D2/D3 domain of FLAG-tagged GP130 (unknown origin) expressed in HEK293 cells assessed as inhibition of rhIL6/Myc-tagged IL6R interaction with GP130 at 10 uM preincubated for 4 hrs followed by stimulation with recombinant human IL6 for 30 mins by co-immunoprecipitation method	Homo sapiens	1		cell-based format	Scientific Literature
10.	ALA4687115	B	Inhibition of GP130 in human A549 cells assessed as decrease in STAT3 phosphorylation at Y705 residue at 3 to 9 uM incubated for 24 hrs by western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
11.	ALA4687116	B	Inhibition of GP130 in human A549 cells assessed as decrease in JAK2 phosphorylation at 3 to 9 uM incubated for 24 hrs by western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
12.	ALA4687117	B	Inhibition of GP130 in human A549 cells assessed as decrease in IL6-induced STAT3 phosphorylation at Y705 residue at 9 uM incubated for 24 hrs by western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
13.	ALA4687118	B	Inhibition of GP130 in human A549 cells assessed as reduction in STAT3 dimer DNA binding activity in nuclear extract in presence of hSIE probe at 3 to 9 uM after 24 hrs by EMSA analysis	Homo sapiens	1		subcellular format	Scientific Literature
14.	ALA4687119	B	Inhibition of GP130 in human A549 cells assessed as reduction in bcl2 protein expression after 24 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
15.	ALA4687120	B	Inhibition of GP130 in human A549 cells assessed as reduction in cyclin-D1 protein expression after 24 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
16.	ALA4687121	B	Inhibition of GP130 in human A549 cells assessed as reduction in survivin protein expression after 24 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature