| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3130530 | Binding | Inhibition of menin-FLAG-tagged MLL-AF9 interaction in mouse bone marrow cells assessed as downregulation of MEIS1 mRNA expression at 6 to 12 uM after 6 days by qRT-PCR analysis | Mus musculus | 1 | ALA3124794 | cell-based format | Scientific Literature | |
| 2. | ALA3130531 | Binding | Inhibition of menin-FLAG-tagged MLL-AF9 interaction in mouse bone marrow cells assessed as downregulation of HOXA9 mRNA expression at 6 to 12 uM after 6 days by qRT-PCR analysis | Mus musculus | 1 | ALA3124794 | cell-based format | Scientific Literature | |
| 3. | ALA3130532 | Binding | Inhibition of menin-FLAG-tagged MLL-AF9 interaction in mouse bone marrow cells assessed as downregulation of HOXA9 mRNA expression at 3 uM after 6 days by qRT-PCR analysis relative to control | Mus musculus | 1 | ALA3124794 | cell-based format | Scientific Literature | |
| 4. | ALA3130533 | Binding | Inhibition of menin-FLAG-tagged MLL-AF9 interaction in mouse bone marrow cells assessed as downregulation of MEIS1 mRNA expression after 6 days by qRT-PCR analysis | Mus musculus | 2 | ALA3124794 | cell-based format | Scientific Literature | |
| 5. | ALA3130534 | Binding | Inhibition of menin-FLAG-tagged MLL-AF9 interaction in mouse bone marrow cells assessed as downregulation of HOXA9 mRNA expression after 6 days by qRT-PCR analysis | Mus musculus | 2 | ALA3124794 | cell-based format | Scientific Literature | |
| 6. | ALA4189778 | Binding | Binding affinity to menin in mouse bone marrow cells harboring MLL-AF9 fusion protein assessed as inhibition of protein interaction with MLL by measuring cell growth inhibition after 7 days by MTT assay | Mus musculus | 29 | ALA4184328 | cell-based format | Scientific Literature |
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