# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3130530 | B | Inhibition of menin-FLAG-tagged MLL-AF9 interaction in mouse bone marrow cells assessed as downregulation of MEIS1 mRNA expression at 6 to 12 uM after 6 days by qRT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
2. | ALA3130531 | B | Inhibition of menin-FLAG-tagged MLL-AF9 interaction in mouse bone marrow cells assessed as downregulation of HOXA9 mRNA expression at 6 to 12 uM after 6 days by qRT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
3. | ALA3130532 | B | Inhibition of menin-FLAG-tagged MLL-AF9 interaction in mouse bone marrow cells assessed as downregulation of HOXA9 mRNA expression at 3 uM after 6 days by qRT-PCR analysis relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA3130533 | B | Inhibition of menin-FLAG-tagged MLL-AF9 interaction in mouse bone marrow cells assessed as downregulation of MEIS1 mRNA expression after 6 days by qRT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
5. | ALA3130534 | B | Inhibition of menin-FLAG-tagged MLL-AF9 interaction in mouse bone marrow cells assessed as downregulation of HOXA9 mRNA expression after 6 days by qRT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
6. | ALA4189778 | B | Binding affinity to menin in mouse bone marrow cells harboring MLL-AF9 fusion protein assessed as inhibition of protein interaction with MLL by measuring cell growth inhibition after 7 days by MTT assay | Mus musculus | 29 | cell-based format | Scientific Literature |