| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA817776 | B | Inhibition of TNF-alpha binding to TNFRc1 | 33 | single protein format | Scientific Literature | |||
| 2. | ALA817777 | B | Compound was tested for inhibition of TNF-alpha binding to TNFRc1 at a concentration of 10 uM | 21 | single protein format | Scientific Literature | |||
| 3. | ALA815618 | B | Inhibitory activity against TNF using [125]TNF at 10e-5 (M) | 1 | single protein format | Scientific Literature | |||
| 4. | ALA845189 | F | Inhibition of TNF-alpha-induced VCAM-1 expression | 79 | assay format | Scientific Literature | |||
| 5. | ALA963876 | B | Binding affinity to TRAK-A | 4 | single protein format | Scientific Literature | |||
| 6. | ALA1250086 | B | Binding affinity to human TNFR1 by surface plasmon resonance method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3414053 | B | Inhibition of TNFR1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3603427 | B | Inhibition of TNFR in human THP1-XBlue cells containing NF-kappaB-inducible SEAP reporter gene assessed as inhibition of TNFalpha-induced TNFR activation incubated at 37 degC for 1 hr by spectrophotometry | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA3744798 | B | Inhibition of human TNFalpha receptor at 10 uM by radioligand binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA3876286 | B | Displacement of [125I]TNF-alpha from TNF-alpha receptor in human U937 cells at 100 uM measured after 120 mins by scintillation counting method relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4187103 | B | Binding affinity to recombinant human TNFalpha receptor at 10 uM after 120 mins by scintillation counting analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4195488 | B | Inhibition of TNFR in TLR null HEK-blue cells assessed as decrease in TNFalpha-stimulated NF-kappaB activation-mediated SEAP production after 24 hrs by Quanti-blue-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4688322 | B | Binding affinity to TNFR1 (unknown origin) assessed as sedimentation coefficient (S) value at 25 uM by ultracentrifugation analysis (Rvb = 2.2 No_unit) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4688323 | B | Binding affinity to TNFR1 (unknown origin) assessed as sedimentation coefficient (S) value at 25 uM in presence of human TNFalpha by ultracentrifugation analysis (Rvb = 2.2 No_unit) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4688327 | B | Binding affinity to TNFR1 (unknown origin) assessed as apparent molecular weight of protein at 25 uM by ultracentrifugation analysis (Rvb = 27 kDa) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4688328 | B | Binding affinity to TNFR1 (unknown origin) assessed as apparent molecular weight of protein at 25 uM in presence of human TNFalpha by ultracentrifugation analysis (Rvb = 27 kDa) | Homo sapiens | 1 | single protein format | Scientific Literature |
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