# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3603427 | Binding | Inhibition of TNFR in human THP1-XBlue cells containing NF-kappaB-inducible SEAP reporter gene assessed as inhibition of TNFalpha-induced TNFR activation incubated at 37 degC for 1 hr by spectrophotometry | Homo sapiens | 7 | ALA3600286 | cell-based format | Scientific Literature | |
2. | ALA3744798 | Binding | Inhibition of human TNFalpha receptor at 10 uM by radioligand binding assay | Homo sapiens | 1 | ALA3739255 | single protein format | Scientific Literature | |
3. | ALA845189 | Functional | Inhibition of TNF-alpha-induced VCAM-1 expression | 79 | ALA1147634 | assay format | Scientific Literature | ||
4. | ALA1250086 | Binding | Binding affinity to human TNFR1 by surface plasmon resonance method | Homo sapiens | 1 | ALA1240299 | single protein format | Scientific Literature | |
5. | ALA3414053 | Binding | Inhibition of TNFR1 (unknown origin) | Homo sapiens | 1 | ALA3407345 | single protein format | Scientific Literature | |
6. | ALA817776 | Binding | Inhibition of TNF-alpha binding to TNFRc1 | 33 | ALA1144966 | single protein format | Scientific Literature | ||
7. | ALA817777 | Binding | Compound was tested for inhibition of TNF-alpha binding to TNFRc1 at a concentration of 10 uM | 21 | ALA1144966 | single protein format | Scientific Literature | ||
8. | ALA815618 | Binding | Inhibitory activity against TNF using [125]TNF at 10e-5 (M) | 1 | ALA1129317 | single protein format | Scientific Literature | ||
9. | ALA963876 | Binding | Binding affinity to TRAK-A | 4 | ALA1139272 | single protein format | Scientific Literature | ||
10. | ALA3876286 | Binding | Displacement of [125I]TNF-alpha from TNF-alpha receptor in human U937 cells at 100 uM measured after 120 mins by scintillation counting method relative to control | Homo sapiens | 3 | ALA3875185 | cell-based format | Scientific Literature | |
11. | ALA4187103 | Binding | Binding affinity to recombinant human TNFalpha receptor at 10 uM after 120 mins by scintillation counting analysis relative to control | Homo sapiens | 1 | ALA4184197 | single protein format | Scientific Literature | |
12. | ALA4195488 | Binding | Inhibition of TNFR in TLR null HEK-blue cells assessed as decrease in TNFalpha-stimulated NF-kappaB activation-mediated SEAP production after 24 hrs by Quanti-blue-based assay | Homo sapiens | 1 | ALA4190396 | cell-based format | Scientific Literature | |
13. | ALA4688322 | Binding | Binding affinity to TNFR1 (unknown origin) assessed as sedimentation coefficient (S) value at 25 uM by ultracentrifugation analysis (Rvb = 2.2 No_unit) | Homo sapiens | 1 | ALA4680302 | single protein format | Scientific Literature | |
14. | ALA4688323 | Binding | Binding affinity to TNFR1 (unknown origin) assessed as sedimentation coefficient (S) value at 25 uM in presence of human TNFalpha by ultracentrifugation analysis (Rvb = 2.2 No_unit) | Homo sapiens | 1 | ALA4680302 | single protein format | Scientific Literature | |
15. | ALA4688327 | Binding | Binding affinity to TNFR1 (unknown origin) assessed as apparent molecular weight of protein at 25 uM by ultracentrifugation analysis (Rvb = 27 kDa) | Homo sapiens | 1 | ALA4680302 | single protein format | Scientific Literature | |
16. | ALA4688328 | Binding | Binding affinity to TNFR1 (unknown origin) assessed as apparent molecular weight of protein at 25 uM in presence of human TNFalpha by ultracentrifugation analysis (Rvb = 27 kDa) | Homo sapiens | 1 | ALA4680302 | single protein format | Scientific Literature |