| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3131107 | B | Inhibition of IL-6Ralpha/GP130 interaction in ER-negative human SUM159 cells overexpressing IL-6 assessed as inhibition of constitutive STAT3 phosphorylation at Y705 at 10 to 30 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3131110 | B | Inhibition of IL-6Ralpha/GP130 interaction in human PANC-1 cells assessed as inhibition of IL-6-induced STAT3 phosphorylation at Y705 preincubated for 30 mins followed by IL-6 induction measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA3131111 | B | Inhibition of IL-6Ralpha/GP130 interaction in ER-negative human SUM159 cells overexpressing IL-6 assessed as inhibition of constitutive STAT3 phosphorylation at Y705 at 15 to 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3131113 | B | Inhibition of IL-6Ralpha/GP130 interaction in human PANC-1 cells assessed as inhibition of IL-6-induced STAT3 phosphorylation at Y705 at 25 uM preincubated for 30 mins followed by IL-6 induction measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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