# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3131107 | Binding | Inhibition of IL-6Ralpha/GP130 interaction in ER-negative human SUM159 cells overexpressing IL-6 assessed as inhibition of constitutive STAT3 phosphorylation at Y705 at 10 to 30 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3124858 | cell-based format | Scientific Literature | |
2. | ALA3131110 | Binding | Inhibition of IL-6Ralpha/GP130 interaction in human PANC-1 cells assessed as inhibition of IL-6-induced STAT3 phosphorylation at Y705 preincubated for 30 mins followed by IL-6 induction measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3124858 | cell-based format | Scientific Literature | |
3. | ALA3131111 | Binding | Inhibition of IL-6Ralpha/GP130 interaction in ER-negative human SUM159 cells overexpressing IL-6 assessed as inhibition of constitutive STAT3 phosphorylation at Y705 at 15 to 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3124858 | cell-based format | Scientific Literature | |
4. | ALA3131113 | Binding | Inhibition of IL-6Ralpha/GP130 interaction in human PANC-1 cells assessed as inhibition of IL-6-induced STAT3 phosphorylation at Y705 at 25 uM preincubated for 30 mins followed by IL-6 induction measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3124858 | cell-based format | Scientific Literature |