# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2187459 | F | Agonist activity at alpha6/alpha3beta2beta3 nAChR in Sprague-Dawley rat striatal synaptosomes assessed as induction of dopamine release | Rattus norvegicus | 7 | ALA2176949 | subcellular format | Scientific Literature | |
2. | ALA2187461 | F | Agonist activity at alpha6/alpha3beta2beta3 nAChR in Sprague-Dawley rat striatal synaptosomes assessed as induction of dopamine release relative to 10 uM nicotine | Rattus norvegicus | 7 | ALA2176949 | subcellular format | Scientific Literature | |
3. | ALA3107446 | B | Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiology method | Rattus norvegicus | 1 | ALA3102714 | cell-based format | Scientific Literature | |
4. | ALA3107564 | B | Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current after 2 to 4 days by voltage clamp electrophysiology method | Rattus norvegicus | 1 | ALA3102714 | cell-based format | Scientific Literature | |
5. | ALA3107570 | B | Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiology method | Rattus norvegicus | 1 | ALA3102714 | cell-based format | Scientific Literature | |
6. | ALA3107575 | B | Antagonist activity at Sprague-Dawley rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiology method | Rattus norvegicus | 1 | ALA3102714 | cell-based format | Scientific Literature | |
7. | ALA4672081 | B | Inhibition of rat alpha6alpha3beta2beta3 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV holding potential by two-electrode voltage-clamp assay relative to control | Rattus norvegicus | 1 | ALA4665854 | cell-based format | Scientific Literature | |
8. | ALA4811728 | B | Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Rattus norvegicus | 6 | ALA4811225 | cell-based format | Scientific Literature |