# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2330202 | B | Inhibition of PRC2 complex (unknown origin) using histone H3 (21 to 44) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenosylmethionine | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
2. | ALA3111734 | B | Inhibition of EZH2/SUZ12/EED complex (unknown origin)-mediated incorporation of methyl group from [3H]-SAM into peptide substrate up to 50 uM by scintillation proximity assay | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
3. | ALA3294386 | B | Inhibition of EZH2 histone methyltransferase activity in EZH2/SUZ12/EED protein complex (unknown origin) using histone H3 peptide/S-adenosylmethionine as substrate after 2 hrs by TR-FRET assay | Homo sapiens | 7 | protein complex format | Scientific Literature | ||
4. | ALA5127869 | B | Inhibition of PRC2 complex of EZH2-EED-SUZ12 (unknown origin) using human nucleosome as substrate incubated for 70 mins in presence of [3H]SAM | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
5. | ALA5228436 | B | Inhibition of EZH2-EED-SUZ12 (unknown origin) complex assessed as nucleosome methylation by radioactivity based assay | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
6. | ALA5237679 | B | Stabilization of PRC2 complex of EZH2-EED-SUZ12 (unknown origin) assessed as thermal stability by measuring increase in melting temperature by thermal shift assay | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
7. | ALA5237680 | B | Binding affinity to PRC2 complex of EZH2-EED-SUZ12 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry method | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
8. | ALA5237681 | B | Inhibition of PRC2 complex of EZH2-EED-SUZ12 (unknown origin) using human nucleosome as substrate incubated for 70 mins in presence of [3H]SAM | Homo sapiens | 1 | protein complex format | Scientific Literature |